Results 61 to 70 of about 108,329 (92)

Crosstalk of Intercellular Signaling Pathways in the Generation of Midbrain Dopaminergic Neurons In Vivo and from Stem Cells

Journal of Developmental Biology, 2019
Dopamine-synthesizing neurons located in the mammalian ventral midbrain are at the center stage of biomedical research due to their involvement in severe human neuropsychiatric and neurodegenerative disorders, most prominently Parkinson’s Disease ...
Claude Brodski, Sandra Blaess, Juha Partanen, Nilima Prakash   +3 more
doaj   +1 more source

Embryonic POU5F1 is Required for Expanded Bovine Blastocyst Formation. [PDF]

, 2018
POU5F1 is a transcription factor and master regulator of cell pluripotency with indispensable roles in early embryo development and cell lineage specification.
Daigneault, Bradford W, Rajput, Sandeep, Ross, Pablo J, Smith, George W   +3 more
core   +2 more sources

Transmission of mitochondrial DNA following assisted reproduction and nuclear transfer [PDF]

, 2006
Review of the articleMitochondria are the organelles responsible for producing the majority of a cell's ATP and also play an essential role in gamete maturation and embryo development.
Alam, Almeida-Santos, Anderson, Ankel-Simons, Barritt, Bavister, Blok, Boulet, Brenner, Brison, Brown, Brown, Campbell, Chang, Chen, Chen, Chinnery, Chung, Cibelli, Cohen, Cortesini, Cui, Cummins, Cummins, Dailey, Danan, Davis, De Block, Dean, Dumollard, Dunbar, D’Aurelio, E.C. Spikings, Eichenlaub-Ritter, Eisen, El Shourbagy, Falkenberg, Fisher, Fisher, Fulka, Gahan, Giles, Graziewicz, Gyllensten, Hammer, Han, Hance, Hanna, Hauswirth, He, Hecht, Hiendleder, Hiendleder, Hiendleder, Holden, Houghton, Humpherys, Inoue, Irwin, J. Alderson, J.C.St. John, Jansen, Kaneda, Keefe, Kenyon, King, Kirches, Klopstock, Koehler, Kondo, Kondo, Kong, Kong, Kraytsberg, Kvist, Laflamme, Larsson, Larsson, Larsson, Larsson, Leese, Lertrit, Lestienne, Levy, Lin, Liu, Liu, Liu, Lloyd, Ludwig, Luetjens, Machaty, Magnusson, Mancuso, Marchington, Margineantu, May-Panloup, McConnell, McCreath, McKenzie, McKenzie, McKenzie, Meirelles, Meirelles, Meirelles, Meusel, Michaels, Monnat, Moyes, Munne, Munsie, Nagao, Naini, Nakamura, Naviaux, Nishi, Nishigaki, Nishimura, Normile, Ojala, Ono, Palermo, Pfeiffer, Piko, Piko, Ponzetto, Poulton, Reynier, Reynier, Rideout, Rubart, Ruiz-Pesini, Sathananthan, Sathananthan, Sato, Satoh, Sazer, Scarpulla, Schon, Schwartz, Seifer, Sherratt, Shitara, Shoubridge, Siciliano, Smith, Sokolova, Spelbrink, Spiropoulos, St. John, St. John, St. John, St. John, St. John, St. John, St. John, St. John, Steinborn, Steinborn, Steuerwald, Stojanovski, Stojkovic, Sturmey, Sun, Sun, Suomalainen, Sutovsky, Sutovsky, Takeda, Takeda, Takeda, Takeuchi, Takeuchi, Taylor, Tessa, Thompson, Tiranti, Trounce, Trounson, Tsaousis, Vajta, Van Blerkom, Van Blerkom, Van Blerkom, Van Goethem, Wakayama, Wallace, Wallace, Wernig, White, White, Wiesner, Wilding, Wilmut, Xu, Yakes, Yang, Yang, Zhang, Zhao, Zouros   +200 more
core   +1 more source

DNA methylation and DNA methyltransferases [PDF]

, 2017
The prevailing views as to the form, function, and regulation of genomic methylation patterns have their origin many years in the past, at a time when the structure of the mammalian genome was only dimly perceived, when the number of protein-encoding ...
Bestor, Timothy H, Boulard, Mathieu, Edwards, John R, Yarychkivska, Olya   +3 more
core   +3 more sources

Sex-specific DNA-replication in the early mammalian embryo

Nature Communications
The timing of DNA replication in mammals is crucial for minimizing errors and influenced by genome usage and chromatin states. Replication timing in the newly formed mammalian embryo remains poorly understood.
Jason Alexander Halliwell, Javier Martin-Gonzalez, Adnan Hashim, John Arne Dahl, Eva R. Hoffmann, Mads Lerdrup   +5 more
doaj   +1 more source

Zebrafish Pou5f1‐dependent transcriptional networks in temporal control of early development

Molecular Systems Biology, 2010
The transcription factor POU5f1/OCT4 controls pluripotency in mammalian ES cells, but little is known about its functions in the early embryo. We used time‐resolved transcriptome analysis of zebrafish pou5f1 MZspg mutant embryos to identify genes ...
Daria Onichtchouk, Florian Geier, Bozena Polok, Daniel M Messerschmidt, Rebecca Mössner, Björn Wendik, Sungmin Song, Verdon Taylor, Jens Timmer, Wolfgang Driever   +9 more
doaj   +1 more source

MITOCHONDRIA IN MAMMALIAN OOCYTES AND EARLY EMBRYOS. A REVIEW ON MORPHOLOGICAL AND FUNCTIONAL STUDIES

Euromediterranean Biomedical Journal, 2018
Mitochondria are the most abundant organelles in mammalian oocytes and early embryos. The central role of mitochondria in the establishment of developmental competence of oocytes and early embryos come out from basic research in experimental models and ...
Manuel Belli
doaj   +1 more source

X-chromosome inactivation mosaicism in the three germ layers and the germ line of the mouse embryo [PDF]

, 1982
Electrophoretic variant forms of the X-linked enzyme phosphoglycerate kinase (PGK-1, E.C.2, 7, 2, 3) have been used to examine X-chromosome mosaicism in tissues from 121/2-day post coitum heterozygous female mouse embryos.
Fosten, M., McMahon, A., Monk, M.
core  

Molecular approaches to mammalian uterine receptivity for conceptus implantation

The Journal of Reproduction and Development
Mammalian reproduction is more inefficient than expected and embryo/conceptus implantation into the maternal endometrium is considered to be a rate-limiting process. Although extensive physiological and structural diversity exists among mammalian species,
Kaiyu KUBOTA
doaj   +1 more source

Involvement of sperm acetylated histones and the nuclear isoform of Glutathione peroxidase 4 in fertilization [PDF]

, 2017
We previously demonstrated that the nuclear form of Glutathione peroxidase 4 (nGPx4) has a peculiar distribution in sperm head, being localized to nuclear matrix and acrosome and that sperm lacking nGPx4 are more prone to decondensation in vitro. In this
Boitani, Carla, Esposito, Valentina, Fiorenza, Maria T., Fuso, Andrea, Lucarelli, Marco, Mangia, Franco, Mularoni, Valentina, Pipolo, Simona, Puglisi, Rossella   +8 more
core   +1 more source