Results 71 to 80 of about 199,433 (310)

Development of Effective Cryopreservation Method for Mammalian Embryo

Journal of Animal Reproduction and Biotechnology, 2014
This study was carried out to evaluate the effects of embryonic stage, cryoprotectant, and freezing-thawing method on the rates of survival and development of the cryopreserved mouse early embryo and finally to establish the cryopreservation method of ...
Hyun Kim, Young Moo Cho, Yeoung-Gyu Ko, Sung Woo Kim, Hwan-Hoo Seong, Keitaro Yamanouchi   +5 more
doaj   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

A 3D mechanical model of the early mammalian embryo [PDF]

, 2009
The early development of the mammalian embryo leads to the formation of a structure composed by an outer layer of polarized cells surrounding an inner mass of nonpolarized cells.
Dard, Nicolas, Glisse, Jérôme, Laforge, Bertrand, Le Guillou, Laurent, Louvet-Vallée, Sophie, Maro, Bernard   +5 more
core   +2 more sources

Haemogenic endocardium contributes to transient definitive haematopoiesis. [PDF]

, 2013
Haematopoietic cells arise from spatiotemporally restricted domains in the developing embryo. Although studies of non-mammalian animal and in vitro embryonic stem cell models suggest a close relationship among cardiac, endocardial and haematopoietic ...
Arshi, Armin, Conway, Simon J., Harmon, Andrew W., Harvey, Richard P., Liu, Xiaoqian, Mikkola, Hanna K. A., Nakano, Atsushi, Nakano, Haruko, Nakano, Haruko, Nakashima, Yasuhiro, Pashmforoush, Mohammad, Sasidharan, Rajkumar, Schwartz, Robert J., Shin, Jae-Ho, van Handel, Ben   +14 more
core   +1 more source

Instructions for Assembling the Early Mammalian Embryo [PDF]

Developmental Cell, 2018
The preimplantation mouse embryo is a simple self-contained system, making it an excellent model to discover how mammalian cells function in real time and in vivo. Work over the last decade has revealed some key morphogenetic mechanisms that drive early development, yielding rudimentary instructions for the generation of a mammalian embryo.
White, Melanie D., Zenker, Jennifer, Bissiere, Stephanie, Plachta, Nicolas   +3 more
openaire   +4 more sources

Optimising image capture for low-light widefield quantitative fluorescence microscopy [PDF]

APL Photon. 10, 031102 (2025)
Low-light optical imaging refers to the use of cameras to capture images with minimal photon flux. This area has broad application to diverse fields, including optical microscopy for biological studies. In such studies, it is important to reduce the intensity of illumination to reduce adverse effects such as photobleaching and phototoxicity that may ...
arxiv   +1 more source

New Perspectives on Semiconducting Conjugated Oligomers for Neuromodulation in Hydra vulgaris

Advanced Materials Interfaces, EarlyView.
Semiconducting organic compounds, thiophene‐based, modify the rhythmic electrical activity of the cnidarian Hydra vulgaris acting on specific neuronal circuits. The ETE‐S trimer also forms electronically conducting wires in the living tissues of the animal.
Giuseppina Tommasini, Mariarosaria De Simone, Martina Blasio, Claudia Zenna, Angela Tino, Eleni Stavrinidou, Silvia Santillo, Claudia Tortiglione   +7 more
wiley   +1 more source

Oocyte specific lncRNA variant Rose influences oocyte and embryo development

Non-coding RNA Research, 2021
Fully grown mammalian oocytes store a large amount of RNA synthesized during the transcriptionally active growth stage. A large part of the stored RNA belongs to the long non-coding class which contain either transcriptional noise or important ...
Rajan Iyyappan, Daria Aleshkina, Linkai Zhu, Zongliang Jiang, Veronika Kinterova, Andrej Susor   +5 more
doaj  

Building Principles for Constructing a Mammalian Blastocyst Embryo

Biology, 2018
The self-organisation of a fertilised egg to form a blastocyst structure, which consists of three distinct cell lineages (trophoblast, epiblast and hypoblast) arranged around an off-centre cavity, is unique to mammals.
Peter L. Pfeffer
doaj   +1 more source

Embryo metabolism : what does it really mean? [PDF]

, 2015
The study of early embryo metabolism has fascinated researchers in the field for nearly a century. Herein, we give a brief account of the general features of embryo metabolism and some consideration of the research performed to reach such conclusions. It
Lewis, Niamh, Sturmey, Roger
core