Differential Expression Of Gap Junction mRNAs And Proteins In The Developing Murine Kidney And In Experimentally Induced Nephric Mesenchymes [PDF]
, 1992 The expression of three gap junction (GJ) proteins, alpha-1 (Cx43), beta-1 (Cx32), and beta-2 (Cx26), and their transcripts were examined during the ontogeny of the mouse and rat kidney. These proteins were expressed in two non-overlapping patterns.
Gilbert, Scott F. +6 more
core +1 more source
Sex determination in mythology and history [PDF]
, 2005 The history of ideas on how the sexes became divided spans at least three thousand years. The biblical account of the origin of Eve, and the opinions of the philosophers of classical Greece, have unexpected bearings on present-day ideas.
Mittwoch, U
core +2 more sources
Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation [PDF]
, 2006 The planar cell polarity (PCP) pathway is conserved throughout evolution, but it mediates distinct developmental processes. In Drosophila, members of the PCP pathway localize in a polarized fashion to specify the cellular polarity within the plane of the
Brinkman, Brendan C. +9 more
core +1 more source
Sex-specific DNA-replication in the early mammalian embryo
Nature CommunicationsThe timing of DNA replication in mammals is crucial for minimizing errors and influenced by genome usage and chromatin states. Replication timing in the newly formed mammalian embryo remains poorly understood.
Jason Alexander Halliwell +5 more
doaj +1 more source
Euromediterranean Biomedical Journal, 2018 Mitochondria are the most abundant organelles in mammalian oocytes and early embryos. The central role of mitochondria in the establishment of developmental competence of oocytes and early embryos come out from basic research in experimental models and ...
Manuel Belli
doaj +1 more source
Vascular remodeling of the mouse yolk sac requires hemodynamic force [PDF]
, 2007 The embryonic heart and vessels are dynamic and form and remodel while functional. Much has been learned about the genetic mechanisms underlying the development of the cardiovascular system, but we are just beginning to understand how changes in heart ...
Chen, Ju +5 more
core +1 more source
Molecular approaches to mammalian uterine receptivity for conceptus implantation
The Journal of Reproduction and DevelopmentMammalian reproduction is more inefficient than expected and embryo/conceptus implantation into the maternal endometrium is considered to be a rate-limiting process. Although extensive physiological and structural diversity exists among mammalian species,
Kaiyu KUBOTA
doaj +1 more source
Zebrafish Pou5f1‐dependent transcriptional networks in temporal control of early development
Molecular Systems Biology, 2010 The transcription factor POU5f1/OCT4 controls pluripotency in mammalian ES cells, but little is known about its functions in the early embryo. We used time‐resolved transcriptome analysis of zebrafish pou5f1 MZspg mutant embryos to identify genes ...
Daria Onichtchouk +9 more
doaj +1 more source
Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during pronuclear development in equine zygotes produced by ICSI [PDF]
, 2017 Background: Global epigenetic reprogramming is considered to be essential during embryo development to establish totipotency. In the classic model first described in the mouse, the genome-wide DNA demethylation is asymmetric between the paternal and the ...
De Schauwer, Catharina +3 more
core +1 more source
Digital microfluidic processing of mammalian embryos for vitrification.
PLoS ONE, 2014 Cryopreservation is a key technology in biology and clinical practice. This paper presents a digital microfluidic device that automates sample preparation for mammalian embryo vitrification.
Derek G Pyne +3 more
doaj +1 more source