Results 81 to 90 of about 199,433 (310)
Terrestrial Planets Formation around Circumbinary Habitable Zone: Inward Migration in the Planetesimal Swarm [PDF]
, 2012 According to the core accretion theory, circumbinary embryos can form only beyond a critical semimajor axis (CSMA). However, due to the relatively high density of solid materials in the inner disk, significant amount of small planetesimals must exist in the inner zone when embryos were forming outside this CSMA.
arxiv +1 more source
Advanced Therapeutics, EarlyView.Antimicrobial resistance necessitates the development of new antibiotics with “resistance‐breaking” properties. In this study, conjugation of polycationic peptides is proven to represent a versatile strategy for the fast and affordable reactivation of daptomycin.
Sari Rasheed +21 more
wiley +1 more source
Cilia, calcium and the basis of left-right asymmetry
BMC Biology, 2012 The clockwise rotation of cilia in the developing mammalian embryo drives a leftward flow of liquid; this genetically regulated biophysical force specifies left-right asymmetry of the mammalian body.
Norris Dominic P
doaj +1 more source
Lack of RNA-DNA oligonucleotide (chimeraplast) mutagenic activity in mouse embryos [PDF]
, 2005 There are numerous reports of the use of RNA-DNA oligonucleoticles (chimeraplasts) to correct point mutations in vitro and in vivo, including the human apolipoprotein E gene (ApoE).
Owen, JS, Simons, JP, Tagalakis, AD
core +1 more source
The growth of planetary embryos: orderly, runaway, or oligarchic? [PDF]
Astron.J. 125 (2003) 942, 2002 We consider the growth of a protoplanetary embryo embedded in a planetesimal disk. We take into account the dynamical evolution of the disk caused by (1) planetesimal-planetesimal interactions, which increase random motions and smooth gradients in the disk, and (2) gravitational scattering of planetesimals by the embryo, which tends to heat up the disk
arxiv +1 more source
FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
Advanced Science, EarlyView.This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang +14 more
wiley +1 more source
Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 542-549, December 2022., 2022 Schematic diagram showing RHAU can bind and unwind the G4 “knots” to modulate embryonic development and post‐natal organ function. Deficiency of RHAU gives rise to embryonic lethality, impaired organogenesis and organ dysfunction. RHAU modulates Nkx2‐5 mRNA and Yap1 mRNA at the post‐transcriptional level and facilitates the transcription of c‐Kit and ...
Chensi Yang +5 more
wiley +1 more source
Repeats as global DNA methylation marker in bovine preimplantation embryos [PDF]
, 2017 DNA methylation undergoes dynamic changes and is a crucial part of the epigenetic regulation during mammalian early development. To determine the DNA methylation levels in bovine embryos, we applied a bisulfite sequencing based method aimed at repetitive
Li, Wenwen, Peelman, Luc, Van Soom, Ann
core +2 more sources
Roles of Kdm6a and Kdm6b in Regulation of Mammalian Neural Regeneration
Advanced Science, EarlyView.This study reveals that Kdm6a plays key roles in repressing either peripheral nervous system (PNS) or central nervous system (CNS) axon regeneration, whereas Kdm6b is not involved in regulating CNS axon regeneration. Moreover, both demethylases are able to regulate CNS neuronal survival after injury, but with non‐overlapping mechanisms.
Shu‐Guang Yang +13 more
wiley +1 more source
Stem Cells International, 2021 Endogenous retroviruses (ERVs) are repetitive sequences in the genome, belonging to the retrotransposon family. During the course of life, ERVs are associated with multiple aspects of chromatin and transcriptional regulation in development and ...
Yangquan Xiang, Hongqing Liang
doaj +1 more source