Results 21 to 30 of about 308,636 (261)

An immunological approach of sperm sexing and different methods for identification of X- and Y-chromosome bearing sperm [PDF]

Veterinary World, 2017
Separation of X- and Y-chromosome bearing sperm has been practiced for selection of desired sex of offspring to increase the profit in livestock industries. At present, fluorescence-activated cell sorter is the only successful method for separation of X-
Shiv Kumar Yadav, Dharmendra Kumar Gangwar, Jarnail Singh, Chiranjeev Kumar Tikadar, V. Vinoth Khanna, Sudha Saini, Sunny Dholpuria, Prabhat Palta, Radhey Shyam Manik, Manoj Kumar Singh, Suresh Kumar Singla   +10 more
doaj   +1 more source

Analysis of DNA methylation profiles during sheep skeletal muscle development using whole-genome bisulfite sequencing

BMC Genomics, 2020
Background DNA methylation is an epigenetic regulatory form that plays an important role in regulating the gene expression and the tissues development.. However, DNA methylation regulators involved in sheep muscle development remain unclear.
Yixuan Fan, Yaxu Liang, Kaiping Deng, Zhen Zhang, Guomin Zhang, Yanli Zhang, Feng Wang   +6 more
doaj   +1 more source

Optimization of a CRISPR/Cas9-mediated Knock-in Strategy at the Porcine Rosa26 Locus in Porcine Foetal Fibroblasts

Scientific Reports, 2017
Genetically modified pigs have important roles in agriculture and biomedicine. However, genome-specific knock-in techniques in pigs are still in their infancy and optimal strategies have not been extensively investigated.
Zicong Xie, Daxin Pang, Kankan Wang, Mengjing Li, Nannan Guo, Hongming Yuan, Jianing Li, Xiaodong Zou, Huping Jiao, Hongsheng Ouyang, Zhanjun Li, Xiaochun Tang   +11 more
doaj   +1 more source

Activation and Inhibition of The Wnt3A Signaling Pathway in Buffalo (Bubalus bubalis) Embryonic Stem Cells: Effects of WNT3A, Bio and Dkk1 [PDF]

International Journal of Fertility and Sterility, 2015
Background This research studies the effects of activation and inhibition of Wnt3A signaling pathway in buffalo (Bubalus bubalis) embryonic stem (ES) cell-like cells.
Mohammad Zandi, Syed Mohamad Shah, Musharifa Muzaffar, Manoj Kumar Singh, Prabhat Palta, Suresh Kumar Singla, Radhey Sham Manik, Manmohan Singh Chauhan   +7 more
doaj   +1 more source

Embryo research [PDF]

Nature, 1990
JOSE ANTONIO ABRISQUETA, VITALINO ALLER
  +9 more sources

Oct4 regulates DNA methyltransferase 1 transcription by direct binding of the regulatory element

Cellular & Molecular Biology Letters, 2018
Background The transcription factor Oct4 plays a pivotal role in the pre-implantation development of the mouse embryo. DNA methyltransferase 1 (Dnmt1) maintains the changes in DNA methylation during mammalian early embryonic development.
Fengrui Wu, Qingqing Wu, Dengkun Li, Yuan Zhang, Rong Wang, Yong Liu, Wenyong Li   +6 more
doaj   +1 more source

Highly efficient RNA-guided base editing in rabbit

Nature Communications, 2018
Base editors can make targeted changes without inducing a double-stranded break. Here, the authors apply the BE3 and ABE7.10 systems to rabbit to create highly efficient targeted base substitutions and various mutation types, and show reduced frequency ...
Zhiquan Liu, Mao Chen, Siyu Chen, Jichao Deng, Yuning Song, Liangxue Lai, Zhanjun Li   +6 more
doaj   +1 more source

The Study of Alternative Splicing Events in Human Induced Pluripotent Stem Cells From a Down's Syndrome Patient

Frontiers in Cell and Developmental Biology, 2021
Down's syndrome (DS) is one of the most commonly known disorders with multiple congenital disabilities. Besides severe cognitive impairment and intellectual disability, individuals with DS also exhibit additional phenotypes of variable penetrance and ...
Yunjie Wang, Yunjie Wang, Zexu Li, Zexu Li, Guanheng Yang, Guanheng Yang, Linlin Cai, Linlin Cai, Fan Yang, Fan Yang, Yaqiong Zhang, Yaqiong Zhang, Yitao Zeng, Yitao Zeng, Qingwen Ma, Qingwen Ma, Fanyi Zeng, Fanyi Zeng, Fanyi Zeng   +18 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

AMH regulates granulosa cell function via ESR2/ p38-MAPK signaling pathway in sheep

Communications Biology
Anti-Müllerian Hormone (AMH), secreted by granulosa cells (GCs) of preantral follicles, regulates early-stage follicle growth by inhibiting the activation of primordial follicles.
Hui Xu, Yu Cai, Hua Yang, Chong Zhang, Wanru Liu, Binru Zhao, Feng Wang, Yanli Zhang   +7 more
doaj   +1 more source