Scientific Reports, 2017 Genetically modified pigs have important roles in agriculture and biomedicine. However, genome-specific knock-in techniques in pigs are still in their infancy and optimal strategies have not been extensively investigated.
Zicong Xie +11 more
doaj +1 more source
The Plant Ontology facilitates comparisons of plant development stages across species [PDF]
, 2019 The Plant Ontology (PO) is a community resource consisting of standardized terms, definitions, and logical relations describing plant structures and development stages, augmented by a large database of annotations from genomic and phenomic studies.
Cooper, Laurel +7 more
core +2 more sources
Gene regulatory network subcircuit controlling a dynamic spatial pattern of signaling in the sea urchin embryo [PDF]
, 2008 We dissect the transcriptional regulatory relationships coordinating the dynamic expression patterns of two signaling genes, wnt8 and delta, which are central to specification of the sea urchin embryo endomesoderm.
Alifragis +34 more
core +3 more sources
Oct4 regulates DNA methyltransferase 1 transcription by direct binding of the regulatory element
Cellular & Molecular Biology Letters, 2018 Background The transcription factor Oct4 plays a pivotal role in the pre-implantation development of the mouse embryo. DNA methyltransferase 1 (Dnmt1) maintains the changes in DNA methylation during mammalian early embryonic development.
Fengrui Wu +6 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Down's syndrome (DS) is one of the most commonly known disorders with multiple congenital disabilities. Besides severe cognitive impairment and intellectual disability, individuals with DS also exhibit additional phenotypes of variable penetrance and ...
Yunjie Wang +18 more
doaj +1 more source
Highly efficient RNA-guided base editing in rabbit
Nature Communications, 2018 Base editors can make targeted changes without inducing a double-stranded break. Here, the authors apply the BE3 and ABE7.10 systems to rabbit to create highly efficient targeted base substitutions and various mutation types, and show reduced frequency ...
Zhiquan Liu +6 more
doaj +1 more source
Detrimental effects of lipopolysaccharides on maturation of bovine oocytes [PDF]
Asian-Australasian Journal of Animal Sciences, 2019 Objective Gram-negative bacteria lipopolysaccharide (LPS) has been reported to be associated with uterine impairment, embryonic resorption, ovarian dysfunction, and follicle retardation.
Shanjiang Zhao +5 more
doaj +1 more source
Analysis of chlorophyll fluorescence reveals stage specific patterns of chloroplast-containing cells during Arabidopsis embryogenesis [PDF]
, 2010 http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000100012&lng=es&nrm=isoThe basic body plan of a plant is established early in embryogenesis when cells differentiate, giving rise to the apical and basal regions of the embryo.
Meisel, Lee +2 more
core +2 more sources
THE IDENTIFICATION OF CHROMOSOMAL POLYMORPHISM IN ONE BREED OF IRAQI SHEEP
The Iraqi Journal of Veterinary Medicine, 1989 A chromosomal analysis of three breeds of Iraqi sheep (Karadi Arabi and Awassi) has been performed on peripheral lymphocytes. The modal chromosome number of all the three breeds was found to be (2n=54XX/54XY) for femal and male respectively.
A. A. Yasseen +3 more
doaj +1 more source
YBX1 mediates alternative splicing and maternal mRNA decay during pre-implantation development
Cell & Bioscience, 2022 Background In mammals, maternal gene products decay and zygotic genome activation (ZGA) during maternal to zygotic transition (MZT) is critical for the early embryogenesis.
Mingtian Deng +6 more
doaj +1 more source