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Single-Step Genomic Prediction of Superovulatory Response Traits in Japanese Black Donor Cows

open access: yesBiology, 2023
We assessed the performance of single-step genomic prediction of breeding values for superovulatory response traits in Japanese Black donor cows. A total of 25,332 records of the total number of embryos and oocytes (TNE) and the number of good embryos ...
Atsushi Zoda   +6 more
doaj   +1 more source

Watching embryos develop [PDF]

open access: yesNature Methods, 2020
Embryonic development is typically hidden from view, but a window preparation technique now sheds light on this phase in the life of a mouse.
openaire   +2 more sources

Comparing Methods to Select Candidates for Re-Genotyping to Impute Higher-Density Genotype Data in a Japanese Black Cattle Population: A Case Study

open access: yesAnimals, 2023
As optimization methods to identify the best animals for dense genotyping to construct a reference population for genotype imputation, the MCA and MCG methods, which use the pedigree-based additive genetic relationship matrix (A matrix) and the genomic ...
Shinichiro Ogawa   +3 more
doaj   +1 more source

A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre

open access: yesNature Communications, 2021
Single cell analysis of early human embryos identifies key changes in pluripotency, the requirement of FGF signalling for embryo survival, and defines a putative anterior-like region of hypoblast cells, providing insights into how early human development
Matteo A. Molè   +18 more
doaj   +1 more source

Oct4 regulates DNA methyltransferase 1 transcription by direct binding of the regulatory element

open access: yesCellular & Molecular Biology Letters, 2018
Background The transcription factor Oct4 plays a pivotal role in the pre-implantation development of the mouse embryo. DNA methyltransferase 1 (Dnmt1) maintains the changes in DNA methylation during mammalian early embryonic development.
Fengrui Wu   +6 more
doaj   +1 more source

Filtered reproductive long non-coding RNAs by genome-wide analyses of goat ovary at different estrus periods

open access: yesBMC Genomics, 2018
Background The goat is an important farm animal. Reproduction is an important process of goat farming. The ovary is the most important reproductive organ for goats.
Yong Liu   +17 more
doaj   +1 more source

Transcriptional defects and reprogramming barriers in somatic cell nuclear reprogramming as revealed by single-embryo RNA sequencing

open access: yesBMC Genomics, 2018
Background Nuclear reprogramming reinstates totipotency or pluripotency in somatic cells by changing their gene transcription profile. This technology is widely used in medicine, animal husbandry and other industries.
Yong Liu   +13 more
doaj   +1 more source

Bisphenol A interferes with lncRNA Fhadlos2 and RUNX3 association in adolescent mouse ovary

open access: yesEcotoxicology and Environmental Safety, 2023
Bisphenol A (BPA) has a number of adverse effects on the reproductive development of females. In particular, the mechanism of disruption of ovarian development in adolescent mice is still unclear.
Yilei Zhang   +9 more
doaj   +1 more source

Stain-free detection of embryo polarization using deep learning

open access: yesScientific Reports, 2022
Polarization of the mammalian embryo at the right developmental time is critical for its development to term and would be valuable in assessing the potential of human embryos.
Cheng Shen   +5 more
doaj   +1 more source

A Single-Cell Atlas of an Early Mongolian Sheep Embryo

open access: yesVeterinary Sciences, 2023
Cell types have been established during organogenesis based on early mouse embryos. However, our understanding of cell types and molecular mechanisms in the early embryo development of Mongolian sheep has been hampered.
Tingyi He   +17 more
doaj   +1 more source

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