Results 31 to 40 of about 547,146 (311)

Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo

Nature Communications, 2017
The molecular trigger that establishes cell polarity in the mammalian embryo is unclear. Here, the authors show that de novo polarisation of the mouse embryo at the 8-cell stage is directed by Phospholipase C and Protein kinase C and occurs in two phases:
Meng Zhu, Chuen Yan Leung, Marta N. Shahbazi, Magdalena Zernicka-Goetz   +3 more
doaj   +1 more source

Omics for understanding the tolerant mechanism of Trichoderma asperellum TJ01 to organophosphorus pesticide dichlorvos

BMC Genomics, 2018
Backgroud Though it is toxic to humans, dichlorvos is a widely used chemical pesticide and plays an important role in the control of plant pests. The application of a combination of the biocontrol agent Trichoderma with dichlorvos may reduce the need for
Qiong Wu, Mi Ni, Guisheng Wang, Qianqian Liu, Meixia Yu, Jun Tang   +5 more
doaj   +1 more source

The effect of cadmium on the bovine in vitro oocyte maturation and early embryo development [PDF]

, 2019
Common pollutants such as heavy metals and cadmium is among those with high environmental concerns. In vivo studies had shown that cadmium (Cd) causes oocyte degeneration and embryo mortality, and lowers pregnancy rates in mammals.
Angerer P., Bires J., Mlynarcikova A., Pisa J., Vrsanska S.   +4 more
core   +1 more source

MicroRNA Signaling in Embryo Development [PDF]

Biology, 2017
Expression of microRNAs (miRNAs) is essential for embryonic development and serves important roles in gametogenesis. miRNAs are secreted into the extracellular environment by the embryo during the preimplantation stage of development. Several cell types secrete miRNAs into biological fluids in the extracellular environment.
Nicole Gross, Jenna Kropp, Hasan Khatib
openaire   +3 more sources

Long non-coding RNAs potentially function synergistically in the cellular reprogramming of SCNT embryos

BMC Genomics, 2018
Background Long non-coding RNAs (lncRNAs), a type of epigenetic regulator, are thought to play important roles in embryonic development in mice, and several developmental defects are associated with epigenetic modification disorders.
Fengrui Wu, Yong Liu, Qingqing Wu, Dengkun Li, Ling Zhang, Xiaoqing Wu, Rong Wang, Di Zhang, Shaorong Gao, Wenyong Li   +9 more
doaj   +1 more source

Integrative Single-Cell Transcriptomic Analysis of Human Fetal Thymocyte Development

Frontiers in Genetics, 2021
Intrathymic differentiation of T lymphocytes begins as early as intrauterine stage, yet the T cell lineage decisions of human fetal thymocytes at different gestational ages are not currently understood. Here, we performed integrative single-cell analyses
Yuchen Li, Yuchen Li, Yuchen Li, Weihong Zeng, Weihong Zeng, Weihong Zeng, Tong Li, Tong Li, Tong Li, Yanyan Guo, Yanyan Guo, Yanyan Guo, Guangyong Zheng, Xiaoying He, Xiaoying He, Lilian Bai, Lilian Bai, Lilian Bai, Guolian Ding, Guolian Ding, Guolian Ding, Li Jin, Li Jin, Xinmei Liu, Xinmei Liu, Xinmei Liu   +25 more
doaj   +1 more source

Maternal lipid profile during early pregnancy and birth weight: A retrospective study

Frontiers in Endocrinology, 2022
IntroductionElevated maternal serum lipid concentrations have been related to an adverse intrauterine environment and lead to abnormal birth weight.ObjectiveIn this study, we aimed to explore the association between maternal lipid profiles during early ...
Si-Meng Zhu, Si-Meng Zhu, Si-Meng Zhu, Han-Qiu Zhang, Han-Qiu Zhang, Han-Qiu Zhang, Cheng Li, Chen Zhang, Chen Zhang, Jia-Le Yu, Jia-Le Yu, Jia-Le Yu, Yan-Ting Wu, He-Feng Huang, He-Feng Huang, He-Feng Huang, He-Feng Huang   +16 more
doaj   +1 more source

Fertilization capacity with rainbow trout DNA-damaged sperm and embryo developmental success [PDF]

, 2010
Mammalian spermatozoa undergo a strong selection process along the female tract to guarantee fertilization by good quality cells, but risks of fertilization with DNA-damaged spermatozoa have been reported.
Ahmadi, Andrabi, Barroso, Baumber, Beirao, Cabrita, Evenson, Flajshans, Fortier, Hakem, Hales, Holt, Hu, Irvine, J Beirão, Jalabert, Jaroudi, Lee, Li, Liao, M P Herráez, Maluszynska, Matsuda, S Martínez-Páramo, S Pérez-Cerezales, Satake, Schulte, Singh, Sun, Tam, Tarin, Yeates   +31 more
core   +1 more source

Integrated Multi-Omics Analysis Reveals the Effect of Maternal Gestational Diabetes on Fetal Mouse Hippocampi

Frontiers in Cell and Developmental Biology, 2022
Growing evidence suggests that adverse intrauterine environments could affect the long-term health of offspring. Recent evidence indicates that gestational diabetes mellitus (GDM) is associated with neurocognitive changes in offspring.
Si-si Luo, Si-si Luo, Ke-xin Zou, Ke-xin Zou, Hong Zhu, Hong Zhu, Yi Cheng, Yi Cheng, Yi-shang Yan, Jian-zhong Sheng, He-feng Huang, He-feng Huang, He-feng Huang, He-feng Huang, Guo-lian Ding, Guo-lian Ding   +15 more
doaj   +1 more source

Composite morphogenesis during embryo development

Seminars in Cell & Developmental Biology, 2021
Morphogenesis drives the formation of functional living shapes. Gene expression patterns and signaling pathways define the body plans of the animal and control the morphogenetic processes shaping the embryonic tissues. During embryogenesis, a tissue can undergo composite morphogenesis resulting from multiple concomitant shape changes.
John, Alphy, Rauzi, Matteo
openaire   +2 more sources