Results 11 to 20 of about 254,276 (267)
Frontiers in Endocrinology, 2021 Mounting evidence has shown that intrauterine hyperglycemia exposure during critical stages of development may be contributing to the increasing prevalence of diabetes.
Hong Zhu +21 more
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Construction of a ceRNA network in polycystic ovary syndrome (PCOS) driven by exosomal lncRNA
Frontiers in Genetics, 2022 Polycystic ovary syndrome (PCOS), a common and frustrating syndrome in women of reproductive age, is characterized by symptoms including hyperandrogenemia, ovulation dysfunction, and polycystic ovaries.
Lilian Bai +11 more
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Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo
Nature Communications, 2017 The molecular trigger that establishes cell polarity in the mammalian embryo is unclear. Here, the authors show that de novo polarisation of the mouse embryo at the 8-cell stage is directed by Phospholipase C and Protein kinase C and occurs in two phases:
Meng Zhu +3 more
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BMC Genomics, 2018 Backgroud Though it is toxic to humans, dichlorvos is a widely used chemical pesticide and plays an important role in the control of plant pests. The application of a combination of the biocontrol agent Trichoderma with dichlorvos may reduce the need for
Qiong Wu +5 more
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MicroRNA Signaling in Embryo Development [PDF]
Biology, 2017 Expression of microRNAs (miRNAs) is essential for embryonic development and serves important roles in gametogenesis. miRNAs are secreted into the extracellular environment by the embryo during the preimplantation stage of development. Several cell types secrete miRNAs into biological fluids in the extracellular environment.
Nicole Gross, Jenna Kropp, Hasan Khatib
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BMC Genomics, 2018 Background Long non-coding RNAs (lncRNAs), a type of epigenetic regulator, are thought to play important roles in embryonic development in mice, and several developmental defects are associated with epigenetic modification disorders.
Fengrui Wu +9 more
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Integrative Single-Cell Transcriptomic Analysis of Human Fetal Thymocyte Development
Frontiers in Genetics, 2021 Intrathymic differentiation of T lymphocytes begins as early as intrauterine stage, yet the T cell lineage decisions of human fetal thymocytes at different gestational ages are not currently understood. Here, we performed integrative single-cell analyses
Yuchen Li +25 more
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Maternal lipid profile during early pregnancy and birth weight: A retrospective study
Frontiers in Endocrinology, 2022 IntroductionElevated maternal serum lipid concentrations have been related to an adverse intrauterine environment and lead to abnormal birth weight.ObjectiveIn this study, we aimed to explore the association between maternal lipid profiles during early ...
Si-Meng Zhu +16 more
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Frontiers in Cell and Developmental Biology, 2022 Growing evidence suggests that adverse intrauterine environments could affect the long-term health of offspring. Recent evidence indicates that gestational diabetes mellitus (GDM) is associated with neurocognitive changes in offspring.
Si-si Luo +15 more
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Composite morphogenesis during embryo development
Seminars in Cell & Developmental Biology, 2021 Morphogenesis drives the formation of functional living shapes. Gene expression patterns and signaling pathways define the body plans of the animal and control the morphogenetic processes shaping the embryonic tissues. During embryogenesis, a tissue can undergo composite morphogenesis resulting from multiple concomitant shape changes.
John, Alphy, Rauzi, Matteo
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