Results 21 to 30 of about 1,437,405 (386)

Complete human day 14 post-implantation embryo models from naive ES cells

open access: yesNature, 2023
The ability to study human post-implantation development remains limited owing to ethical and technical challenges associated with intrauterine development after implantation^ 1 . Embryo-like models with spatially organized morphogenesis and structure of
Bernardo Oldak   +26 more
semanticscholar   +1 more source

Unique and independent role of the GABAB1 subunit in embryo implantation and uterine decidualization in mice

open access: yesGenes and Diseases, 2021
Embryo implantation and decidualization are crucial for successful pregnancy, which include multiple genes and signaling pathways, while the precise mechanism regarding embryo implantation and decidualization has yet to be explored.
Wenhao Chen   +4 more
doaj   +1 more source

Pluripotent stem cell-derived model of the post-implantation human embryo

open access: yesNature, 2023
Co-culture of wild-type human embryonic stem cells with two types of extraembryonic-like cell engineered to overexpress specific transcription factors results in an embryoid model that recapitulates multiple features of the post-implantation human embryo.
Bailey A. T. Weatherbee   +6 more
semanticscholar   +1 more source

MicroRNAs in the Regulation of Endometrial Receptivity for Embryo Implantation

open access: yesInternational Journal of Molecular Sciences, 2022
Development of endometrial receptivity is crucial for successful embryo implantation and pregnancy initiation. Understanding the molecular regulation underpinning endometrial transformation to a receptive state is key to improving implantation rates in ...
Manizha Shekibi, Sophea Heng, G. Nie
semanticscholar   +1 more source

Immune Tolerance of Embryo Implantation and Pregnancy: The Role of Human Decidual Stromal Cell- and Embryonic-Derived Extracellular Vesicles

open access: yesInternational Journal of Molecular Sciences, 2022
Embryo–endometrial communication plays a critical role in embryo implantation and the establishment of a successful pregnancy. Successful pregnancy outcomes involve maternal immune modulation during embryo implantation.
Hsien-Ming Wu   +3 more
semanticscholar   +1 more source

microRNAs as A Biomarker to Predict Embryo Quality Assessment in In Vitro Fertilization [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2023
Embryo selection for in vitro fertilization (IVF) is an effort to increase the success rate of embryo implantation. Factors influencing the success of embryo implantation include embryo quality, endometrial receptivity, embryo characteristics, and ...
Kresna Mutia   +4 more
doaj   +1 more source

Dissecting peri-implantation development using cultured human embryos and embryo-like assembloids

open access: yesbioRxiv, 2023
Studies of cultured embryos have provided insights into human peri-implantation development. However, detailed knowledge of peri-implantation lineage development as well as underlying mechanisms remains obscure. Using 3D-cultured human embryos, herein we
Zongyong Ai   +24 more
semanticscholar   +1 more source

Primary specification of blastocyst trophectoderm by scRNA-seq: New insights into embryo implantation

open access: yesScience Advances, 2022
Mechanisms of implantation such as determination of the attachment pole, fetal-maternal communication, and underlying causes of implantation failure are largely unexplored.
Dan Liu   +20 more
semanticscholar   +1 more source

The impacts of the number of prefreeze and postthaw blastomeres on embryo implantation potential

open access: yesMedicine, 2020
To systematically analyze the potential of embryo implantation through comparison between the number of surviving blastomeres, the growth, and implantation rate.
Yu-jiang Wang   +8 more
semanticscholar   +1 more source

The role of Wnt/β-catenin-lin28a/let-7 axis in embryo implantation competency and epithelial-mesenchymal transition (EMT)

open access: yesCell Communication and Signaling, 2020
Background The pre-implantation embryo in a competent status and post-implantation fully differentiation of the inner cell mass (ICM) and trophectoderm (TE) are prerequisites of successful implantation. Type I embryonic epithelial-mesenchymal transition (
Qian Li, Juanzi Shi, Weimin Liu
doaj   +1 more source

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