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Complete human day 14 post-implantation embryo models from naive ES cells
The ability to study human post-implantation development remains limited owing to ethical and technical challenges associated with intrauterine development after implantation^ 1 . Embryo-like models with spatially organized morphogenesis and structure of
Bernardo Oldak+26 more
semanticscholar +1 more source
Embryo implantation and decidualization are crucial for successful pregnancy, which include multiple genes and signaling pathways, while the precise mechanism regarding embryo implantation and decidualization has yet to be explored.
Wenhao Chen+4 more
doaj +1 more source
Pluripotent stem cell-derived model of the post-implantation human embryo
Co-culture of wild-type human embryonic stem cells with two types of extraembryonic-like cell engineered to overexpress specific transcription factors results in an embryoid model that recapitulates multiple features of the post-implantation human embryo.
Bailey A. T. Weatherbee+6 more
semanticscholar +1 more source
MicroRNAs in the Regulation of Endometrial Receptivity for Embryo Implantation
Development of endometrial receptivity is crucial for successful embryo implantation and pregnancy initiation. Understanding the molecular regulation underpinning endometrial transformation to a receptive state is key to improving implantation rates in ...
Manizha Shekibi, Sophea Heng, G. Nie
semanticscholar +1 more source
Embryo–endometrial communication plays a critical role in embryo implantation and the establishment of a successful pregnancy. Successful pregnancy outcomes involve maternal immune modulation during embryo implantation.
Hsien-Ming Wu+3 more
semanticscholar +1 more source
microRNAs as A Biomarker to Predict Embryo Quality Assessment in In Vitro Fertilization [PDF]
Embryo selection for in vitro fertilization (IVF) is an effort to increase the success rate of embryo implantation. Factors influencing the success of embryo implantation include embryo quality, endometrial receptivity, embryo characteristics, and ...
Kresna Mutia+4 more
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Dissecting peri-implantation development using cultured human embryos and embryo-like assembloids
Studies of cultured embryos have provided insights into human peri-implantation development. However, detailed knowledge of peri-implantation lineage development as well as underlying mechanisms remains obscure. Using 3D-cultured human embryos, herein we
Zongyong Ai+24 more
semanticscholar +1 more source
Mechanisms of implantation such as determination of the attachment pole, fetal-maternal communication, and underlying causes of implantation failure are largely unexplored.
Dan Liu+20 more
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The impacts of the number of prefreeze and postthaw blastomeres on embryo implantation potential
To systematically analyze the potential of embryo implantation through comparison between the number of surviving blastomeres, the growth, and implantation rate.
Yu-jiang Wang+8 more
semanticscholar +1 more source
Background The pre-implantation embryo in a competent status and post-implantation fully differentiation of the inner cell mass (ICM) and trophectoderm (TE) are prerequisites of successful implantation. Type I embryonic epithelial-mesenchymal transition (
Qian Li, Juanzi Shi, Weimin Liu
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