Results 31 to 40 of about 111,508 (346)

Gene Expression Profiling of Corpus luteum Reveals Important Insights about Early Pregnancy in Domestic Sheep [PDF]

open access: yes, 2020
The majority of pregnancy loss in ruminants occurs during the preimplantation stage, which is thus the most critical period determining reproductive success. Here, we performed a comparative transcriptome study by sequencing total mRNA from corpus luteum
Honkatukia, Mervi   +5 more
core   +1 more source

Secreted MicroRNA to Predict Embryo Implantation Outcome: From Research to Clinical Diagnostic Application

open access: yesFrontiers in Cell and Developmental Biology, 2020
Embryo implantation failure is considered a leading cause of infertility and a significant bottleneck for in vitro fertilization (IVF) treatment. Confirmed factors that lead to implantation failure involve unhealthy embryos, unreceptive endometrium, and ...
Wei Zhou   +3 more
doaj   +1 more source

The Complicated Effects of Extracellular Vesicles and Their Cargos on Embryo Implantation

open access: yesFrontiers in Endocrinology, 2021
As a rate-limiting step in pregnancy, embryo implantation is highly dependent on intercellular communication. Extracellular vesicles (EVs) are newly identified to be important in the course of intercellular communication.
Nan-Xing Jiang   +3 more
doaj   +1 more source

Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation

open access: yesJournal of Nanobiotechnology, 2023
Most pregnancy losses worldwide are caused by implantation failure for which there is a lack of effective therapeutics. Extracellular vesicles are considered potential endogenous nanomedicines because of their unique biological functions.
Linjun Hong   +16 more
doaj   +1 more source

Modeling human trophoblast, the placental epithelium at the maternal fetal interface. [PDF]

open access: yes, 2020
Appropriate human trophoblast lineage specification and differentiation is crucial for the establishment of normal placentation and maintenance of pregnancy. However, due to the lack of proper modeling systems, the molecular mechanisms of these processes
Bui, Tony   +3 more
core   +1 more source

Prediction model for day 3 embryo implantation potential based on metabolites in spent embryo culture medium

open access: yesBMC Pregnancy and Childbirth, 2023
Background Metabolites in spent embryo culture medium correlate with the embryo’s viability. However, there is no widely accepted method using metabolite dada to predict successful implantation.
Rong Liang   +8 more
doaj   +1 more source

Assessment of Embryo-Induced Transcriptomic Changes in Hamster Uterus Using RNA-Seq

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: The mouse is widely used as an animal model for studying human embryo implantation. However, the mouse is unique in that both ovarian progesterone and estrogen are critical to implantation, whereas in the majority of species (e.g.
Ming-Yu Huang   +5 more
doaj   +1 more source

Human endometrial receptivity and embryo-endometrium interactions [PDF]

open access: yes, 2011
Infertility is an increasing medical and social problem affecting more than 10% of couples worldwide. Many underlying causes of human infertility have been overcome by assisted reproductive techniques; nevertheless, the implantation process remains one
Altmäe, Signe
core   +1 more source

Uterine receptivity, embryo attachment, and embryo invasion: Multistep processes in embryo implantation

open access: yesReproductive Medicine and Biology, 2019
Background Recurrent implantation failure is a critical issue in IVF‐ET treatment. Successful embryo implantation needs appropriate molecular and cellular communications between embryo and uterus.
Yamato Fukui   +6 more
doaj   +1 more source

VIP treatment prevents embryo resorption by modulating efferocytosis and activation profile of maternal macrophages in the CBAxDBA resorption prone model [PDF]

open access: yes, 2016
Successful embryo implantation occurs followed by a local pro-inflammatory response subsequently shifted toward a tolerogenic one. VIP (vasoactive intestinal peptide) has embryotrofic, anti-inflammatory and tolerogenic effects.
Calo, Guillermina   +7 more
core   +1 more source

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