Results 251 to 260 of about 250,859 (356)

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

Advanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu, Guoqing Jing, Shujuan Wu, Min Yuan, Yingyue Dong, Xue Chen, Huimin Zhou, Hailong Gong, Jing Zuo, Xiaojing Wu, Xuemin Song   +10 more
wiley   +1 more source

Correlation of the sperm DNA fragmentation index with semen parameters and its impact on fresh embryo transfer outcomes-a retrospective study. [PDF]

PeerJ
Wan XJ, Huang M, Yu M, Ding T, Huang Z, Zhang Z, Wu X, Tan J.   +7 more
europepmc   +1 more source

Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

Advanced Science, EarlyView.
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang, Qi Wang, Dongkun Kang, Shijia Wang, Yanli Jiang, Jian‐Zhi Wang, Chen Ming, Rong Liu, Jianlan Gu, Xiaochuan Wang   +9 more
wiley   +1 more source

Overcoming Cervical Stenosis: A Case Study of Transmyometrial Embryo Transfer in Infertility Treatment.

J Pharm Bioallied Sci
Shah D, More A, Choudhary N, Kalaskar G, Dhamija P.   +4 more
europepmc   +1 more source

Letrozole ovulation regimen for frozen-thawed embryo transfer in women with polycystic ovary syndrome: a muti-centre randomised controlled trial. [PDF]

Reprod Biol Endocrinol
Xie Y, Li P, Hao G, Deng W, Zhao J, Gao S, Deng B, Li Y, Deng M, Yuan Y, Fan Q, Zhang N, Zhao Z, Shi Y.   +13 more
europepmc   +1 more source

Studies on Application of Ultrasound for Selection of Carcass Traits on Donor Cow for Embryo Transfer in Japanese Black Cattle

, 1995
Tomoyuki YAKUSHIJI, Hiroshi Harada, Nobuhiro KITA, Peregrino G. Duran   +3 more
openalex   +2 more sources

USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang, Xueying Wang, Shanhong Lu, Yan Gao, Gangcai Zhu, Guo Li, Zongnan Yu, Junwei Hou, Helei Yan, Wenhui Yuan, Xin Zhang, Mien‐Chie Hung, Zhifeng Liu, Yong Liu   +13 more
wiley   +1 more source

Cytotoxic Lesion of the Corpus Callosum Related to Migraine With Aura Triggered by In Vitro Fertilization and Embryo Transfer: A Case Report. [PDF]

Cureus
Akinci Y, Anash G.
europepmc   +1 more source

[Book Review of] \u3cem\u3eLaw and Ethics of A.I.D. and Embryo Transfer\u3c/em\u3e, Ciba Foundation Symposium J7 [PDF]

, 1974
Lebel, Robert Roger
core   +1 more source

Compressed Cells Facilitate Adhesion Through Glycocalyx

Advanced Science, EarlyView.
This study quantifies how cell compression and confinement triggers cell adhesion. Under low compression, integrins dominate cell adhesion to extracellular matrix (ECM) proteins, whereas the glycocalyx contributes weak unspecific adhesion. With increasing compression, the glycocalyx increases its unspecific adhesion to ECM and non‐ECM proteins and can ...
Xiaole Wang, Jonne Helenius, Daniel J. Müller, Nico Strohmeyer   +3 more
wiley   +1 more source