Non-Canonical Maternal <i>WNT4</i> Activates Canonical Zygotic <i>WNT8C</i> for Early Embryonic Development in Chicken. [PDF]
Hwang YS, Kim SK, Han JY.
europepmc +1 more source
ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec +18 more
wiley +1 more source
miR-203 facilitates timely cell fate transitions via epigenetic modulation during early embryogenesis. [PDF]
González-Martínez J +14 more
europepmc +1 more source
Axial length, myopia progression, and myopic maculopathy in Stickler syndrome
Abstract Purpose We lack knowledge on the potentially progressive nature of and the prevalence of complications to myopia as a characteristic trait of Stickler syndrome. Methods This cross‐sectional study combines ophthalmic examination and medical record data on Danish patients with genetically confirmed Stickler syndrome type 1 (COL2A1) and type 2 ...
Kirstine B. Boysen +4 more
wiley +1 more source
Establishment of a refined somatic embryogenesis protocol and light-spectrum-based acclimatization in Caladium bicolor 'White'. [PDF]
Dehestani-Ardakani M +3 more
europepmc +1 more source
The Embryonic Development of the Cotylean Polyclad Phrikoceros jannetae
ABSTRACT Polyclads exhibit distinct developmental modes ranging from direct to indirect development, with several transitional stages also recognised. The existence of an indirect developmental mode in polyclads with a planktonic life history stage in the form of a free‐swimming larva is unique among all free‐living flatworms and makes polyclads a ...
Mehrez Gammoudi +6 more
wiley +1 more source
Identification of Auxin, Cytokinin, Transcription Factors, and Other Zygotic Embryogenesis-Related Genes in <i>Persea americana</i>: A Transcriptomic-Based Study. [PDF]
Quintana-Escobar AO +5 more
europepmc +1 more source
Chemotherapy‐induced WNT ligand secretion by bone marrow (BM) stroma drives acute lymphoblastic leukaemia (ALL) chemoresistance. WNT pathway inhibition disrupts this cross‐talk and restores therapeutic response, highlighting WNT inhibitors as a promising strategy to prevent relapse in ALL.
Foteini Kalampalika +4 more
wiley +1 more source
GA-binding protein alpha ensures proper blastocyst development by suppressing SMAD3-mediated transforming growth factor-beta signaling. [PDF]
Liao J, Ma Y, Liu Y, Guo R, Yao H.
europepmc +1 more source
KRAB Zinc‐Finger Protein ZNF205 Promotes Hepatocellular Carcinoma via p53 Pathway Repression
ZNF205 functions as a critical oncogenic regulator in hepatocellular carcinoma (HCC), where it interacts with p53 and functionally suppresses its transcriptional activity by competitively inhibiting p53 binding to target gene promoters. This p53 inactivation mechanism critically contributes to tumor progression in HCC. ABSTRACT The tumor suppressor p53
Xiaofen Huang +15 more
wiley +1 more source

