Advances in GPCRs Associated With Wnt Signaling Within the Auditory System
Medicine Bulletin, EarlyView.ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang +3 more
wiley +1 more source
Correction: Prevalence, mutation distribution, and economic burden of thalassemia in China: a systematic review and regional analysis. [PDF]
Arch Public HealthCai A +7 more
europepmc +1 more source
The Role of HUWE1 on Mouse Neural Cell Proliferation and Zebrafish Neurodevelopment
Medicine Bulletin, EarlyView.ABSTRACT The HECT, UBA, and WWE domain‐containing E3 ubiquitin protein ligase 1 (HUWE1) gene is located on the X chromosome and has been implicated in neurodevelopmental disorders. However, the mechanisms by which HUWE1 dosage affects nervous system development remain poorly understood. In this study, we demonstrate that HUWE1 overexpression suppresses
Haojuan Wu +10 more
wiley +1 more source
Comparative embryogenesis of two salp species reveals rogue development and evolutionary divergence from sessile tunicates. [PDF]
PLoS BiolLebel M, Alié A, Lemaire P, Tiozzo S.
europepmc +1 more source
The Journal of Pathology, EarlyView.Abstract Canalicular adenoma (CA) is a benign salivary gland tumor predominantly affecting the upper lip and is characterized by monomorphic epithelial cells arranged in branching cords within a loose and vascularized stroma. Unlike pleomorphic adenoma (PA), CA lacks a chondroid matrix and exhibits specific histological features, such as high cuboidal ...
Ziyad Alsugair +8 more
wiley +1 more source
A cellular basis for the hourglass pattern in vertebrate embryogenesis. [PDF]
Nat CommunDamatac A +3 more
europepmc +1 more source
A Comprehensive Review of the Genetic Etiology and Management of Orofacial Clefts
Pediatric Discovery, EarlyView.ABSTRACT Cleft lip (CL) and cleft palate (CP), collectively referred to as orofacial clefts (OFCs), are among the most common birth defects and can have significant effects on speech, nutrition, and physical and psychosocial development. Manifestation, classification, and treatment plans of OFCs are diverse and not standardized.
Emily Kim +3 more
wiley +1 more source
Single-Cell Transcriptomic Analysis Reveals Early Transcriptional Heterogeneity of Cardiac-Associated Cell Populations During Zebrafish Embryogenesis. [PDF]
Biology (Basel)Khalaf SN +4 more
europepmc +1 more source
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Mark Rebeiz +9 more
wiley +1 more source
Reconsidering how to dry orthodox seeds for improved ex situ conservation outcomes
PLANTS, PEOPLE, PLANET, EarlyView.Ex situ seed conservation is an essential tool in our efforts to conserve wild and cultivated plant diversity, as mentioned in the Global Strategy for Plant Conservation and the Sustainable Development Goals. While there are established standards which seed banks follow, it is important that we continue to evaluate protocols and optimize processes ...
Fiona R. Hay +7 more
wiley +1 more source