Results 51 to 60 of about 51,733 (247)

Morphological and histological changes during the somatic embryogenesis of mangosteen

, 2011
Induction of somatic embryogenesis in leaf explants from young mangosteen seedlings using different concentrations and combinations of 6-benzylaminopurine (BAP) and thidiazuron (TDZ) was investigated.
M. N. Normah, E. R. Rohani, I. Ismanizan, M. Elviana   +3 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Cyclin-Dependent Kinase 5 Regulatory Subunit Associated Protein 3: Potential Functions and Implications for Development and Disease

Frontiers in Oncology, 2021
Cyclin-dependent kinase 5 (CDK5) regulatory subunit associated protein 3 (CDK5RAP3, also named as C53 or LZAP) was initially identified as a binding protein of CDK5 activator p35.
Linna Sheng, Linna Sheng, Jiaxuan Li, Shengfang Rao, Zhijun Yang, Yonghong Huang   +5 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Regulatory principles governing the maternal-to-zygotic transition: insights from Drosophila melanogaster [PDF]

Open Biology, 2018
The onset of metazoan development requires that two terminally differentiated germ cells, a sperm and an oocyte, become reprogrammed to the totipotent embryo, which can subsequently give rise to all the cell types of the adult organism.
Danielle C. Hamm, Melissa M. Harrison
doaj   +1 more source

Sexual Dimorphism of the Heart: Genetics, Epigenetics, and Development

Frontiers in Cardiovascular Medicine, 2021
The democratization of genomic technologies has revealed profound sex biases in expression patterns in every adult tissue, even in organs with no conspicuous differences, such as the heart.
Daniel F. Deegan, Priya Nigam, Nora Engel   +2 more
doaj   +1 more source

Somatic embryogenesis, cryopreservation, and in vitro mutagenesis in cyclamen

, 2015
The cyclamen is a member of the family Primulaceae and consists of 22 species, originated from the Mediterranean Basin. Due to inbreeding depression, abortive zygotic embryo formation, and varying ploidy levels, vegetative production is frequently ...
Seker G., Gamze Seker, Teixeira Da Silva J.A., Jaime A. Teixeira da Silva, Mohammad Tagipur E., Ehsan Mohammad Tagipur, Yesim Yalcin Mendi, Yalcin Mendi Y.   +7 more
core   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Foxo3-mediated physiological cell competition ensures robust tissue patterning throughout vertebrate development

Nature Communications
Unfit cells with defective signalling or gene expression are eliminated through competition with neighbouring cells. However, physiological roles and mechanisms of cell competition in vertebrates remain unclear.
Kanako Matsumoto, Yuki Akieda, Yukinari Haraoka, Naoki Hirono, Hiroshi Sasaki, Tohru Ishitani   +5 more
doaj   +1 more source

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

Advanced Science, EarlyView.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li, Haijun Zhang, Jieya Zhou, Shiyu Yang, Jingmei Cha, Gaofeng Yan, Shuhua Zhao, Bingyu Mao, Pengcheng Ma   +8 more
wiley   +1 more source