Results 41 to 50 of about 164,194 (304)

Plant Embryogenesis [PDF]

open access: yes, 2021
Despite intense investigation of plant embryogenesis, there are still various open questions in this fascinating field. For example, our knowledge is still poor in relation to the spatiotemporal dynamics and the regulatory mechanisms of various embryonic

core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Cyclin-Dependent Kinase 5 Regulatory Subunit Associated Protein 3: Potential Functions and Implications for Development and Disease

open access: yesFrontiers in Oncology, 2021
Cyclin-dependent kinase 5 (CDK5) regulatory subunit associated protein 3 (CDK5RAP3, also named as C53 or LZAP) was initially identified as a binding protein of CDK5 activator p35.
Linna Sheng   +5 more
doaj   +1 more source

Somatic embryogenesis, cryopreservation, and in vitro mutagenesis in cyclamen

open access: yes, 2015
The cyclamen is a member of the family Primulaceae and consists of 22 species, originated from the Mediterranean Basin. Due to inbreeding depression, abortive zygotic embryo formation, and varying ploidy levels, vegetative production is frequently ...
Seker G.   +7 more
core   +1 more source

Molecular characterization and expression pattern of AFPIV during embryogenesis in gibel carp(Carassiu auratus gibelio) [PDF]

open access: yes, 2009
As a new type of AFPs, AFPIV has been firstly identified in longhorn sculpin (Myoxocephalus octodecimspinosus), and in recent years, its cDNA and amino acid sequence have been reported, and its pancreatic synthesis has been firstly reported in polar fish.
Liu, Jing-Xia   +3 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Regulatory principles governing the maternal-to-zygotic transition: insights from Drosophila melanogaster [PDF]

open access: yesOpen Biology, 2018
The onset of metazoan development requires that two terminally differentiated germ cells, a sperm and an oocyte, become reprogrammed to the totipotent embryo, which can subsequently give rise to all the cell types of the adult organism.
Danielle C. Hamm, Melissa M. Harrison
doaj   +1 more source

Sexual Dimorphism of the Heart: Genetics, Epigenetics, and Development

open access: yesFrontiers in Cardiovascular Medicine, 2021
The democratization of genomic technologies has revealed profound sex biases in expression patterns in every adult tissue, even in organs with no conspicuous differences, such as the heart.
Daniel F. Deegan   +2 more
doaj   +1 more source

A Versatile Microfluidic Extrusion‐Based Hydrogel Platform for Self‐Organization and Long‐Term Maintenance of Engineered 3D Lymphatic Endothelium

open access: yesAdvanced Healthcare Materials, EarlyView.
Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi   +8 more
wiley   +1 more source

Foxo3-mediated physiological cell competition ensures robust tissue patterning throughout vertebrate development

open access: yesNature Communications
Unfit cells with defective signalling or gene expression are eliminated through competition with neighbouring cells. However, physiological roles and mechanisms of cell competition in vertebrates remain unclear.
Kanako Matsumoto   +5 more
doaj   +1 more source

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