Results 161 to 170 of about 848,551 (267)

Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery

Leukemia, 2006
J. Ratajczak, K. Miękus, M. Kucia, Jin Zhang, R. Reca, P. Dvořák, M. Ratajczak   +6 more
semanticscholar   +1 more source

DKK3 Initially Preserves Acinar Integrity Through MEK‐Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan, Elodie Roger, Lukas Perkhofer, Eleni Zimmer, Thomas F.E. Barth, Julia P. Mosler, Anna Härle, Stephanie E. Weissinger, Nadine T. Gaisa, Peter Möller, Nico Fischer, Chantal Allgöwer, J.‐Matthias Löhr, Dirk Grimm, Thomas Seufferlein, Stefan Liebau, Ninel Azoitei, Michael K. Melzer, Frank Arnold, Johann Gout, Alexander Kleger   +20 more
wiley   +1 more source

Decision letter: Non-canonical TAF complexes regulate active promoters in human embryonic stem cells

, 2012

openalex   +1 more source

Transplantation of human embryonic stem cell-derived retinal pigment epithelial cells (MA09-hRPE) in macular degeneration [PDF]

, 2019
Tina Guanting Qiu
openalex   +1 more source

Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture.

Developmental Biology, 2000
M. Amit, M. Carpenter, M. Inokuma, C. Chiu, C. Harris, M. Waknitz, J. Itskovitz‐Eldor, J. Thomson   +7 more
semanticscholar   +1 more source

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids

Advanced Science, EarlyView.
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang, Tsering Yangzom, Ning Lu, Shenglong Deng, Xianglu Xiao, Guang Yang, Kristina Xiao Liang   +6 more
wiley   +1 more source

Stub1 maintains proteostasis of master transcription factors in embryonic stem cells

Md Mahfuz Al Mamun, Muhammad Riaz Khan, Yifu Zhu, Yuwei Zhang, Shuai Zhou, Ran Xu, Ihtisham Bukhari, Rick F. Thorne, Jinming Li, Xu Dong Zhang, Guangzhi Liu, Song Chen, Mian Wu, Xiaoyuan Song   +13 more
openalex   +1 more source

AICAR Sustains J1 Mouse Embryonic Stem Cell Self-Renewal and Pluripotency by Regulating Transcription Factor and Epigenetic Modulator Expression [PDF]

, 2013
Xiaoyan Shi, Yongyan Wu, Zhiying Ai, Xin Liu, Liping Yang, Juan Du, Jingjing Shao, Zekun Guo, Yong Zhang   +8 more
openalex   +1 more source

m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells.

Cell Stem Cell, 2014
Pedro J. Batista, B. Molinie, Jinkai Wang, K. Qu, Jiajing Zhang, Lingjie Li, D. Bouley, Ernesto Lujan, Bahareh Haddad, Kaveh Daneshvar, Ava C. Carter, Ryan A. Flynn, Chan Zhou, K. Lim, P. Dedon, Marius Wernig, Alan C. Mullen, Yi Xing, Cosmas C. Giallourakis, Howard Y. Chang   +19 more
semanticscholar   +1 more source

Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair

Advanced Science, EarlyView.
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao, Huailong An, Cong Fan, Qingsu Lan, Hongyu Zhong, Yun Zhang, Libo Zhou, Panpan Hao   +7 more
wiley   +1 more source