Results 171 to 180 of about 1,123,946 (363)
Production of a germ-line chimeric mouse derived from newly established embryonic stem cells.
Sadahiro Azuma, Yutaka Toyoda
openalex +2 more sources
Gene conversion during vector insertion in embryonic stem cells [PDF]
Paul Hasty+2 more
openalex +1 more source
Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair
This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng+8 more
wiley +1 more source
Derivation of melanocytes from embryonic stem cells in culture [PDF]
Toshiyuki Yamane+4 more
openalex +1 more source
The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li+3 more
wiley +1 more source
By investigating auditory hyperexcitability in a mouse model for hereditary deafness, this study identified a subpopulation of afferent neurons of the auditory nerve marked by Otogl expression. Despite their apparently normal hearing, Otogl+/− mice display poor activation of afferent neurons processing loud sounds and an elevation of the middle the ear
Mathilde Gagliardini+24 more
wiley +1 more source
Objective: Prompt and effective wound repair is an essential strategy to promote recovery and prevent infection in patients with various types of trauma.
Tian-Qi Ma+14 more
doaj
Segmental genomic replacement in embryonic stem cells by double lox targeting [PDF]
Serguei Soukharev+2 more
openalex +1 more source
Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function
CYTOR is a pro‐myogenic ncRNA in skeletal muscle. Here, chemical probing of CYTOR, coupled with functional cellular assays identifies exon 2 as an independent myogenic RNA domain. Chemical engineering of CYTOR exon 2 RNA improves pharmacologic properties, including RNA stability and cell‐autonomous immunogenicity.
Zeinabou Niasse‐Sy+6 more
wiley +1 more source
NF2 is Essential for Human Endoderm Development
This study demonstrates that NF2, moesin‐ezrin‐radixin like (MERLIN) tumor suppressor (NF2) is essential for human endoderm formation. NF2 knockout human induced pluripotent stem cells fail to form endoderm both in vitro and in vivo due to yes‐associated protein 1 (YAP1) nuclear translocation, redirecting differentiation toward myofibroblast‐like cells.
Minjin Jeong+5 more
wiley +1 more source