Results 181 to 190 of about 566,277 (353)

An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells [PDF]

open access: bronze, 2008
Jonghwan Kim   +4 more
openalex   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

open access: yesAdvanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li   +11 more
wiley   +1 more source

The role of METTL3 in transposable elements regulation and 2C-like program induction in mouse embryonic stem cell. [PDF]

open access: yesCell Regen
Chen X   +12 more
europepmc   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

open access: yesAdvanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen   +11 more
wiley   +1 more source

Generation of implant-type tissue-engineered cartilage from human embryonic stem cell-derived chondrocytes. [PDF]

open access: yesRegen Ther
Huang YC   +11 more
europepmc   +1 more source

28 Successful gene editing of human embryonic stem cells to generate a novel CF airway epithelial model

open access: bronze, 2017
Sara Cuevas Ocaña   +4 more
openalex   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

open access: yesAdvanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao   +11 more
wiley   +1 more source

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