Results 181 to 190 of about 1,123,946 (363)

Complete Meiosis from Embryonic Stem Cell-Derived Germ Cells In Vitro.

open access: yesCell Stem Cell, 2016
Quan Zhou   +14 more
semanticscholar   +1 more source

CK2B Induces CD8+ T‐Cell Exhaustion through HDAC8‐Mediated Epigenetic Reprogramming to Limit the Efficacy of Anti‐PD‐1 Therapy in Non‐Small‐Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
αPD‐1 therapy has left an indelible mark in the field of NSCLC treatment; however, its efficacy is limited in clinical practice owing to the effector T‐cell exhaustion. These findings underscore CK2B as a promising target for overcoming the exhaustion of effector CD8+ T cells, thereby enhancing the efficacy of αPD‐1 and adoptive cell therapies in NSCLC.
Shaochuan Liu   +15 more
wiley   +1 more source

Embryonic stem cell factor FOXD3 (Genesis) defects in gastrointestinal stromal tumors. [PDF]

open access: yesEndocr Relat Cancer, 2023
Faucz FR   +15 more
europepmc   +1 more source

Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome

open access: yesNature Genetics, 2015
S. Schoenfelder   +21 more
semanticscholar   +1 more source

From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis

open access: yesAdvanced Science, EarlyView.
This work utilizes spatial transcriptomics to map the transcriptional landscape of adenomyosis with obvious invagination structure from the invaginating site to deep lesions. By integrating with single‐cell RNA sequencing, this study elucidates the molecular features of invagination, invasion, and fibrosis, and finds the major participants and vital ...
Boyu Li   +19 more
wiley   +1 more source

First-in-human clinical study of an embryonic stem cell product for urea cycle disorders. [PDF]

open access: yesStem Cell Res Ther
Umezawa A   +38 more
europepmc   +1 more source

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