Results 211 to 220 of about 1,123,946 (363)

Influence and Optimization of Diverse Culture Systems on Chicken Embryonic Stem Cell Culture. [PDF]

open access: yesGenes (Basel)
Ren W   +13 more
europepmc   +1 more source

Mouse embryonic stem cell-derived motor neurons are susceptible to ferroptosis. [PDF]

open access: yesFEBS Open Bio, 2023
Martinez AM   +4 more
europepmc   +1 more source

m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells.

open access: yesCell Stem Cell, 2014
Pedro J. Batista   +19 more
semanticscholar   +1 more source

ZNHIT3 Regulates Translation to Ensure Cell Lineage Differentiation in Mouse Preimplantation Development

open access: yesAdvanced Science, EarlyView.
Box C/D snoRNP complex regulates protein translation. This study identifies ZNHIT3 as a key component of the complex and ensures normal protein expression, including transcription factors orchestrating cell fate commitment, during early mouse embryogenesis.
Guanghui Yang, Qiliang Xin, Jurrien Dean
wiley   +1 more source

To unwind the biological knots: The DNA/RNA G‐quadruplex resolvase RHAU (DHX36) in development and disease

open access: yesAnimal Models and Experimental Medicine, Volume 5, Issue 6, Page 542-549, December 2022., 2022
Schematic diagram showing RHAU can bind and unwind the G4 “knots” to modulate embryonic development and post‐natal organ function. Deficiency of RHAU gives rise to embryonic lethality, impaired organogenesis and organ dysfunction. RHAU modulates Nkx2‐5 mRNA and Yap1 mRNA at the post‐transcriptional level and facilitates the transcription of c‐Kit and ...
Chensi Yang   +5 more
wiley   +1 more source

Mouse mutants from chemically mutagenized embryonic stem cells [PDF]

open access: green, 2000
Robert J. Munroe   +8 more
openalex   +1 more source

Accumulation of Damaging Lipids in the Arf1‐Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia

open access: yesAdvanced Science, EarlyView.
Arf1 defects activate the AKT‐mTORC1‐SREBP1‐FASN pathway to increase lipid synthesis and disrupt ER‐mitochondrial‐lysosomal homeostasis in neurons. Impaired mitochondria secrete damaged mtDNA via mitochondria‐derived extracellular vesicles, which is phagocytosed by the microglia and activated inflammation signaling.
Xu Li   +10 more
wiley   +1 more source

ANGPTL8 deficiency attenuates lipopolysaccharide-induced liver injury by improving lipid metabolic dysregulation

open access: yesJournal of Lipid Research
Liver injury is closely related to poor outcomes in sepsis patients. Current studies indicate that sepsis is accompanied by metabolic disorders, especially those related to lipid metabolism.
Ying Feng   +12 more
doaj  

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