Results 221 to 230 of about 1,293,017 (382)

Chromosome-specific aberrations, rather than general aneuploidy, may drive mouse embryonic stem cell-derived teratoma metastasis. [PDF]

Stem Cell Res Ther
Montilla-Rojo J, Hillenius S, Eleveld TF, Salvatori DCF, Looijenga LHJ.   +4 more
europepmc   +1 more source

m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells.

Cell Stem Cell, 2014
Pedro J. Batista, B. Molinie, Jinkai Wang, K. Qu, Jiajing Zhang, Lingjie Li, D. Bouley, Ernesto Lujan, Bahareh Haddad, Kaveh Daneshvar, Ava C. Carter, Ryan A. Flynn, Chan Zhou, K. Lim, P. Dedon, Marius Wernig, Alan C. Mullen, Yi Xing, Cosmas C. Giallourakis, Howard Y. Chang   +19 more
semanticscholar   +1 more source

PSMD14 Stabilizes SLC7A11 to Ameliorate Glucocorticoid‐Induced Osteoporosis by Suppressing Osteocyte Ferroptosis

Advanced Science, EarlyView.
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi, Qian Tang, Sunren Sheng, Hongyi Jiang, Chen Jin, Chencheng Zhou, Chenglong Xie, Lin Zheng, Di Zhang, Hui Xu, Cong Xu, Haiwei Ma, Guangheng Xiang, Wenfei Ni, Xiaoyun Pan, Lei Yang, Huazi Xu, Yu Qian, Aimin Wu, Xiangyang Wang, Gang Zheng   +20 more
wiley   +1 more source

Protocols for the application of human embryonic stem cell-derived neurons for aging modeling and gene manipulation. [PDF]

STAR Protoc
Zhang H, Sun S, Izpisua Belmonte JC, Liu GH, Wang S, Zhang W, Qu J.   +6 more
europepmc   +1 more source

Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery

Leukemia, 2006
J. Ratajczak, K. Miękus, M. Kucia, Jin Zhang, R. Reca, P. Dvořák, M. Ratajczak   +6 more
semanticscholar   +1 more source

Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA

Advanced Science, EarlyView.
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin, Runyu Cao, Xuemei Bai, Jiahua Yuan, Wanwei Sun, Yi Zheng, Xiaopeng Qi, Wei Zhao, Bingyu Liu, Chengjiang Gao   +9 more
wiley   +1 more source

Prolactin drives cortical neuron maturation and dendritic development during murine embryonic stem cell differentiation. [PDF]

Front Cell Dev Biol
Martinez-Alarcon O, Colin-Lagos D, Ramirez-Meza X, Castilla A, Hernandez-Montes G, Flores-Garza E, Lopez-Saavedra A, Avila-Gonzalez D, Martinez-Juarez A, Molina-Hernández A, Diaz-Martinez NE, Portillo W, Diaz NF.   +12 more
europepmc   +1 more source

Role of reactive oxygen species and phosphatidylinositol 3‐kinase in cardiomyocyte differentiation of embryonic stem cells [PDF]

, 2000
Heinrich Sauer, Gohar Rahimi, Jürgen Hescheler, Maria Wartenberg   +3 more
openalex   +1 more source

Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors

Cell, 2006
Kazutoshi Takahashi, S. Yamanaka
semanticscholar   +1 more source

Confined Migration Drives Stem Cell Differentiation

Advanced Science, EarlyView.
Human mesenchymal stem cell (hMSC) homing to sites of regeneration requires navigation through mechanically confining extracellular matrix environments, inducing rapid and dramatic morphological adaptation. By exposing hMSCs to specific levels of physiological confinement, it is demonstrated that confinement can induce osteogenesis, and that this fate ...
Xu Gao, Yixuan Li, Jia Wen Nicole Lee, Jianxuan Zhou, Vaishnavi Rangaraj, Jennifer Marlena, Andrew W. Holle   +6 more
wiley   +1 more source