Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells
L. Boyer +13 more
semanticscholar +1 more source
RAD21L1 is upregulated in human Sertoli cells to be transited to become spermatogonial stem cells by overexpressing DAZ family three genes. RAD21L1 is sufficient and effective for reprogramming Sertoli cells into human spermatogonial stem cells with high safety through DNA methylation.
Caimei He +4 more
wiley +1 more source
Prolactin drives cortical neuron maturation and dendritic development during murine embryonic stem cell differentiation. [PDF]
Martinez-Alarcon O +12 more
europepmc +1 more source
A Cre-lox recombination system for the targeted integration of circular yeast artificial chromosomes into embryonic stem cells [PDF]
Linda Call
openalex +1 more source
Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang +9 more
wiley +1 more source
Chromosome-specific aberrations, rather than general aneuploidy, may drive mouse embryonic stem cell-derived teratoma metastasis. [PDF]
Montilla-Rojo J +4 more
europepmc +1 more source
Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao +7 more
wiley +1 more source
Embryonic stem cell-derived small extracellular vesicles alleviate lead-induced cochlear spiral ganglion neurons injury by activating PI3 K/AKT signaling pathway. [PDF]
Wang L +11 more
europepmc +1 more source
Isolation of a primate embryonic stem cell line.
J. Thomson +6 more
semanticscholar +1 more source

