Results 261 to 270 of about 350,335 (318)

CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning

Advanced Science, EarlyView.
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang, Zexi Chen, Yuanxiang Miao, Zuolin Shen, Deyu Cai, Shijie Tang, Yun Xue, Weifeng Guo, Hongbin Ji, Jian Liu, Kazuyuki Aihara, Luonan Chen   +11 more
wiley   +1 more source

Rat embryonic stem cell-based <i>in vitro</i> testing platform for mammalian embryo toxicology at pre- and post-implantation stages. [PDF]

Front Toxicol
Quadalti C, Moretti M, Ferrazzi F, Calzà L, Giardino L, Baldassarro VA.   +5 more
europepmc   +1 more source

Chromosome-specific aberrations, rather than general aneuploidy, may drive mouse embryonic stem cell-derived teratoma metastasis. [PDF]

Stem Cell Res Ther
Montilla-Rojo J, Hillenius S, Eleveld TF, Salvatori DCF, Looijenga LHJ.   +4 more
europepmc   +1 more source

Tracking Insulin- and Glucagon-Expressing Cells In Vitro and In Vivo Using a Double-Reporter Human Embryonic Stem Cell Line. [PDF]

Diabetes
Mar S, Filatov E, Sasaki S, Mojibian M, Zhang D, Yang A, Nian C, Lynn FC.   +7 more
europepmc   +1 more source

Human embryonic stem cell-derived immunity-and-matrix-regulatory cells promote endometrial repair and fertility restoration in IUA rats. [PDF]

Stem Cell Res Ther
Cao Y, Wu J, Huang J, Fan X, Zhang Y, Li L, Dai Y.   +6 more
europepmc   +1 more source

Correction: CXCL13 suppresses liver regeneration through the negative regulation of HGF signaling

Cell Death and Disease
Qun Zhao, Jingyi Wu, Mengyuan Feng, Anjie Zhang, Liwei Fu, Jinglin Chen, Lian Li, Fangzhou Li, Tingting Li, Shu Jin, Shengbao Li, Xianjun Yu   +11 more
doaj   +1 more source

RNA Surveillance Factor SMG5 Is Essential for Mouse Embryonic Stem Cell Differentiation. [PDF]

Biomolecules
Chen C, Wei Y, Jiang X, Li T.
europepmc   +1 more source

Signalling, cell cycle and pluripotency in embryonic stem cells

Trends in Cell Biology, 2002
Pluripotent mouse embryonic stem (ES) cells can be expanded in large numbers in vitro owing to a process of symmetrical self-renewal. Self-renewal entails proliferation with a concomitant suppression of differentiation.
Tom Burdon, Austin Smith, Pierre Savatier   +2 more
exaly   +2 more sources

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Embryonic Stem Cells

Stem Cells and Development, 2007
Stem cells are unique cell populations with the ability to choose between self-renewal and differentiation. Embryonic stem (ES) cells have the ability to form any fully differentiated cell of the body. To date, only three species of mammals have yielded long-term cultures of self-renewing ES cells- mice, monkeys, and humans.
Atindriya, Biswas, Robert, Hutchins
openaire   +2 more sources