Results 291 to 300 of about 566,277 (353)

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

Advanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao, Jin Gao, Keling Wang, Yufeng Liu, Peijin Han, Hong Pan, Xiaofeng Yang, Qianlan Yin, Dating Zhong, Lu Ye, Qi Deng, Lingling Gao, Xiaoyu Tu, Dequan Wang, Yuming Lu   +14 more
wiley   +1 more source

Advances in development of long-term embryonic stem cell-like cultures from a marine fish, Sciaenops ocellatus. [PDF]

Curr Res Food Sci
Walsh CJ, Rhody N, Main KL, Restivo J, Tarnecki AM.   +4 more
europepmc   +1 more source

The effect of human embryonic stem cell-derived extracellular vesicles (hESEVs) on Müller cells and their potential use for retinal regeneration

, 2016
Debora B. Farber
openalex   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Regulation of glucose metabolism: Effects on oocyte, preimplantation embryo, assisted reproductive technology and embryonic stem cell. [PDF]

Heliyon
Xiong YY, Zhu HY, Shi RJ, Wu YF, Fan Y, Jin L.   +5 more
europepmc   +1 more source

Correction: CRISPR/Cas9-mediated activation of NR5A1 steers female human embryonic stem cell-derived bipotential gonadal-like cells towards a steroidogenic cell fate. [PDF]

J Ovarian Res
Danti L, Lundin K, Sepponen K, Yohannes DA, Kere J, Tuuri T, Tapanainen JS.   +6 more
europepmc   +1 more source

Correction: CXCL13 suppresses liver regeneration through the negative regulation of HGF signaling

Cell Death and Disease
Qun Zhao, Jingyi Wu, Mengyuan Feng, Anjie Zhang, Liwei Fu, Jinglin Chen, Lian Li, Fangzhou Li, Tingting Li, Shu Jin, Shengbao Li, Xianjun Yu   +11 more
doaj   +1 more source

Dissolution of ribonucleoprotein condensates by the embryonic stem cell protein L1TD1. [PDF]

Nucleic Acids Res
Jin SW, Seong Y, Yoon D, Kwon YS, Song H.   +4 more
europepmc   +1 more source

The hanging-heart chip: A portable microfluidic device for high-throughput generation of contractile embryonic stem cell-derived cardiac spheroids. [PDF]

Bioeng Transl Med
Lai PT, He CK, Li CH, Matahum J, Tang CY, Hsu CH.   +5 more
europepmc   +1 more source

Dynamics of microRNA secreted via extracellular vesicles during the maturation of embryonic stem cell-derived retinal pigment epithelium. [PDF]

J Extracell Biol
Pollalis D, Nair GKG, Leung J, Bloemhof CM, Bailey JK, Pennington BO, Kelly KR, Khan AI, Yeh AK, Sundaram KS, Clegg DO, Peng CC, Xu L, Georgescu C, Wren JD, Lee SY.   +15 more
europepmc   +1 more source