Results 201 to 210 of about 506,868 (329)

Inducible Site-Directed Recombination in Mouse Embryonic Stem Cells

, 1996
Yong Zhang, Caroline Riesterer, A.-M. Ayrall, Fred Sablitzky, Trevor D. Littlewood, Michael Reth   +5 more
openalex   +1 more source

Establishment and Chimera Analysis of 129/SvEv- and C57BL/6-Derived Mouse Embryonic Stem Cell Lines [PDF]

, 2000
Wojtek Auerbach, Judy H. Dunmore, Victoria Fairchild-Huntress, Qing Fang, Anna B. Auerbach, Dennis Huszar, Alexandra L. Joyner   +6 more
openalex   +1 more source

Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 Phase

Advanced Science, EarlyView.
Fusing the VP16 domain to OCT4 and SOX2 (OvSvK) enhances iPSC generation by activating downstream targets, including those regulating the cell cycle. This accelerates reprogramming by shortening the G1 phase and reducing H3K27me3 levels. Modulating Ccnd1, Cdkn2a, and Ccne1 improves efficiency, linking cell cycle to epigenetic remodeling.
Lin Guo, Jiechun Lin, Qiwen Ren, Hao Sun, Yanhua Wu, Haofei Ge, Xiaolan Wu, Lihui Lin, Lining Liang, Changpeng Li, He Liu, Yuangbang Mai, Shilong Chu, Jiadong Liu, Jing Liu, Jiekai Chen, Duanqing Pei, Hui Zheng   +17 more
wiley   +1 more source

Dual-Selection Strategy for Generating Knock-Out Lines of Human Embryonic Stem Cells. [PDF]

J Cell Mol Med
Zhou Z, Tong L, Chen Y, Wang R, Shen Y, Chen D.   +5 more
europepmc   +1 more source

Targeted integration of DNA using mutant lox sites in embryonic stem cells

, 1997
Kimi Araki, Masatake Araki, K Yamamura
openalex   +1 more source

Separate Proliferation Kinetics of Fibroblast Growth Factor-Responsive and Epidermal Growth Factor-Responsive Neural Stem Cells within the Embryonic Forebrain Germinal Zone [PDF]

, 2000
David J. Martens, Vincent Tropepe, Derek van der Kooy   +2 more
openalex   +1 more source

A Novel Theranostic Strategy for Malignant Pulmonary Nodules by Targeted CECAM6 with 89Zr/131I‐Labeled Tinurilimab

Advanced Science, EarlyView.
This study investigates the integrated diagnostic and therapeutic strategy utilizing 89Zr/131I‐labeled tinurilimab for the management of malignant lung nodules, with a particular focus on lung adenocarcinoma (LUAD). CEACAM6, which is highly expressed in most LUAD patients, activates the Src/FAK signaling pathway, thereby promoting cell proliferation ...
Chongyang Chen, Keying Zhu, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Min Yang   +8 more
wiley   +1 more source

The regulatory role of m6A modification in the maintenance and differentiation of embryonic stem cells

Genes and Diseases
As the most prevalent and reversible internal epigenetic modification in eukaryotic mRNAs, N6-methyladenosine (m6A) post-transcriptionally regulates the processing and metabolism of mRNAs involved in diverse biological processes.
Jin Zhang, Lingling Tong, Yuchen Liu, Xiang Li, Jiayi Wang, Ruoxin Lin, Ziyu Zhou, Yunbing Chen, Yanxi Chen, Yirong Liu, Di Chen   +10 more
doaj  

ERK phosphorylates ESRRB to regulate the self-renewal and differentiation of mouse embryonic stem cells. [PDF]

Stem Cell Reports
Duan X, Zhang Q, Gao L, Ling B, Du X, Chen L.   +5 more
europepmc   +1 more source

Mouse mutants from chemically mutagenized embryonic stem cells [PDF]

, 2000
Robert J. Munroe, Rebecca A. Bergstrom, Qing Yin Zheng, Brian Libby, Richard S. Smith, Simon W. M. John, Kerry J. Schimenti, Victoria L. Browning, John C. Schimenti   +8 more
openalex   +1 more source