Results 71 to 80 of about 808,443 (353)

Hyaluronan and Hyaluronidase, which is better for embryo development? [PDF]

, 2016
Our aim was to examine size-specific effects of Hyaluronan (HA) on preimplantation embryo development. We investigated the effects of Hyalovet (HA, 500–750 kDa; the size produced by HA synthase-3, which is abundant in the oviduct), or HA treated with ...
Ali A. Fouladi-Nashta, Aruffo, Aviles, Bastow, Bergqvist, Block, Bourguignon, Choudhary, Csoka, Dicker, Fenwick, Fouladi-Nashta, Furnus, Furnus, Georgiou, Hahnel, Hess, Kabir A. Raheem, Lane, Laurent, Lesley, Lloyd, Marei, Marei, Mariani, Matwee, Mazdak Salavati, Mehta, Mohey-Elsaeed, Muhammad Khalid, Neira, Oesterreicher, Ohno-Nakahara, Pandey, Pushpakumara, Raheem, Robinson, Rozen, Russell, Ryan, Saliba, Schmidt, Seytanoglu, Stern, Stevenson, Tienthai, Tina Tremaine, Tombolan, Toole, Torner, Ulbrich, Waleed F.A. Marei, Wang, Wathes, Watson, Way, Weigel, Xu, Yevdokimova, Yoon   +59 more
core   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Embryo Implantation

Developmental Biology, 2000
A lesson learned from modern developmental biology is the striking degree of conservation of strategies and molecules used to program developmental events in species as diverse as insects, birds, amphibians, and mammals. Nonetheless, mammals retain distinctions with regard to the strategies used to protect and nourish their offspring during development,
Carson, Daniel D., Bagchi, Indrani, Dey, Sudhandsu K., Enders, Allen C., Fazleabas, Asgerally T., Lessey, Bruce A., Yoshinaga, Koji   +6 more
openaire   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Warm stratification combined with organic manure application enhances seed germination and improves Cycas revoluta growth and development

Advances in Horticultural Science
Cycas revoluta (Sago palm) is one of the widespread ornamental plant, used as an indoor and outdoor plant. Seed propagation is extremely hard and time consuming, given the physical dormancy imposed by hard coat.
Jalila Benjelloun, Sarah Bouzroud, Younes Zaid, Abdelkarim Guedira, Abdelaziz Smouni   +4 more
doaj   +1 more source

SOMITE NUMBER EVOLUTION DURING EARLY EMBRYOGENESIS IN CHICKEN EMBRYOS FROM TRANSYLVANIAN NAKED NECK AND PLYMOUTH ROCK BREEDS

Scientific Papers Animal Science and Biotechnologies, 2023
In Romania, the Transylvanian Naked Neck hen breed is considered to be an “endangered” population, reason for which we consider that a special attention should have been given until now. Plymouth Rock breed was imported for the first time to Romania from
D. DRONCA, N. PĂCALĂ, I. BENCSIK, LAVINIA ȘTEF, RODICA CĂPRIŢĂ, T. OROIAN, MIHAELA IVANCIA, LILIANA BOCA   +7 more
doaj  

Genetic Normalization of Differentiating Aneuploid Human Embryos [PDF]

, 2011
Early embryogenesis involves a series of dynamic processes, many of which are currently not well described or understood. Aneuploidy and aneuploid mosaicism, a mixture of aneuploid and euploid cells within one embryo, in early embryonic development are ...
Andrew Barker, Andrew Benner, Garry Cutting, Kevin Richter, Khanh-Ha Nguyen, Paul Brezina, Raymond Anchan, Ric Ross, William Kearns   +8 more
core   +1 more source

Early stages of retinal development depend on Sec13 function [PDF]

, 2013
Summary ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Cavodeassi, Florencia, Feng, Yi, Schmidt, Katy, Stephens, David J   +3 more
core   +3 more sources

Uterine receptivity, embryo attachment, and embryo invasion: Multistep processes in embryo implantation [PDF]

Reproductive Medicine and Biology, 2019
AbstractBackgroundRecurrent implantation failure is a critical issue in IVF‐ET treatment. Successful embryo implantation needs appropriate molecular and cellular communications between embryo and uterus. Rodent models have been used intensively to understand these mechanisms.MethodsThe molecular and cellular mechanisms of embryo implantation were ...
Yamato Fukui, Yasushi Hirota, Mitsunori Matsuo, Mona Gebril, Shun Akaeda, Takehiro Hiraoka, Yutaka Osuga   +6 more
openaire   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source