Results 91 to 100 of about 3,399,190 (337)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Riding behavior-based HMIs for motorcycle safety (A comparative study of alert and real-time feedback systems)

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing
Motorcycle assistance systems have been an increasing focus of research in recent years to promote safer riding practices and mitigate motorcycle-related accidents.
Kifle Hailu GEBRETSADIK, Keisuke SUZUKI
doaj   +1 more source

Minimizing treatment-induced emergence of antibiotic resistance in bacterial infections

open access: green, 2022
Mathew Stracy   +14 more
openalex   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Integrating Bioinformatics Analysis with RT-qPCR Experimental Validation to Investigate Immune Cell and Telomere-Related Biomarkers in Chronic Obstructive Pulmonary Disease

open access: yesInternational Journal of COPD
Shengwei Wang, Weiwei Tang, Haixia Yang Department of Emergence Medicine, Nanjing Brain Hospital, Nanjing, Jiangsu, 210029, People’s Republic of ChinaCorrespondence: Haixia Yang, Email yanghx8801@163.comPurpose: Chronic obstructive pulmonary disease ...
Wang S, Tang W, Yang H
doaj  

Prognostic value of systemic immune-inflammation index in the diagnosis of preeclampsia

open access: yesHeliyon
Background: Preeclampsia is a serious complication of pregnancy with negative consequences for the mother and fetus. It was aimed to investigate whether the systemic immune inflammation index is a parameter that will facilitate the diagnosis of ...
Mucahit Kapci   +5 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Simulation of a flux emergence event and comparison with observations by Hinode

open access: yes, 2009
We study the observational signature of flux emergence in the photosphere using synthetic data from a 3D MHD simulation of the emergence of a twisted flux tube. Several stages in the emergence process are considered.
A. Lagg   +43 more
core   +1 more source

Nonlinear effects of wealth inequality on economic growth: evidence from a semiparametric panel analysis of low-income countries

open access: yesDevelopment Studies Research
Growing disparities in asset ownership and capital accumulation have raised concerns about the role of wealth inequality in shaping long-term development, particularly in low-income countries. Although the inequality–growth nexus has been widely studied,
Bocar Sidi Konaté, Said Hanchane
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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