Results 101 to 110 of about 1,408,830 (315)

Prevalence and Genetic Diversity of Bat Hepatitis B Viruses in Bat Species Living in Gabon

Viruses
Hepatitis B virus (HBV) infection leads to around 800,000 deaths yearly and is considered to be a major public health problem worldwide. However, HBV origins remain poorly understood.
Danielle S. Koumba Mavoungou, Linda Bohou Kombila, Neil M. Longo Pendy, Schedy E. Koumba Moukouama, Sonia Etenna Lekana-Douki, Gaël D. Maganga, Eric M. Leroy, Avelin F. Aghokeng, Nadine N’dilimabaka   +8 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Response of Three Chloris elata Populations to Herbicides Sprayed in Pre- and Post-Emergence [PDF]

, 2018
: In agricultural areas of Brazil, where there is no establishment of cover crops in the off-season and in fruit orchards, an increase in Chloris elata infestations, syn. Chloris polydactyla, has been observed.
CORREIA, N. M., N.M. CORREIA (4648261), RESENDE, Í., RESENDE,Í., Í. RESENDE (5717012), CORREIA,N.M.   +5 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

An analysis of norm emergence in Axelrod's model [PDF]

, 2010
Norms are a valuable mechanism for establishing coherent cooperative behaviour in decentralised systems in which no central authority exists. One of the most influential formulations of norm emergence was proposed by Axelrod, who defined a model of norms
Mahmoud, Samhar, Keppens, Jeroen, Griffiths, Nathan, Luck, Michael (Michael M.)   +3 more
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Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Aetiology and Outcomes of Suspected Infections of the Central Nervous System in Children in Mbarara, Uganda

Scientific Reports, 2017
Infections of the central nervous system (CNS) are severe conditions, leading to neurological sequelae or death. Knowledge of the causative agents is essential to develop guidelines for case management in resource-limited settings.
Anne-Laure Page, Yap Boum II, Elizabeth Kemigisha, Nicolas Salez, Deborah Nanjebe, Céline Langendorf, Said Aberrane, Dan Nyehangane, Fabienne Nackers, Emmanuel Baron, Rémi Charrel, Juliet Mwanga-Amumpaire   +11 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The Ontology of Complex Systems: Wimsatt on Emergence

openThis dissertation aims to offer a perspective on Wimsatt's work, emphasizing its originality in addressing ontological issues related to emergence. The first section provides a concise overview of Wilson's concept of Weak Emergence, serving as common
LONGATO, ORSO LODOVICO
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