Results 101 to 110 of about 3,349,217 (305)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

“Noninvasive predictive marker for esophageal variceal bleeding”

open access: yesBMC Gastroenterology
Objective Esophageal varices are common in cirrhosis with portal hypertension; some patients face high risk of life-threatening esophageal variceal bleeding (EVB).
Shuo Zhang   +3 more
doaj   +1 more source

Update on tick-borne pathogens detection methods within ticks

open access: yesCurrent Research in Parasitology and Vector-Borne Diseases
Ticks are known vectors of various pathogens, including bacteria, parasites and viruses, that impact both animal and human health. Improving knowledge of the distribution of tick-borne pathogens, combined with their early detection in ticks, are ...
Eva Krupa   +3 more
doaj   +1 more source

ACUTE ARTICULAR SYNDROME. THE CONCEPT OF EMERGENCY CARE IN RHEUMATOLOGY

open access: yesНаучно-практическая ревматология, 2018
The absence of a current emergency care system for rheumatic patients makes the solution of this problem relevant. Objective: to create and test a health care system for patients with acute articular syndrome (AAS) and to analyze the distribution of ...
A. S. Povzun, V. I. Mazurov
doaj   +1 more source

Causal Emergence and Epiphenomenal Emergence [PDF]

open access: yesErkenntnis, 2018
According to one conception of strong emergence, strongly emergent properties are nomologically necessitated by their base properties and have novel causal powers relative to them. In this paper, I raise a difficulty for this conception of strong emergence, arguing that these two features (i.e., nomological necessitation and causal novelty) are ...
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

New Approaches to the Circle of Sense and Nonsense

open access: yesPhilosophies
I will briefly discuss the history of research-related projects that Mark Burgin and I worked on together. I will then discuss our joint research related to the circle of sense and nonsense.
Bill Seaman
doaj   +1 more source

A Morphology of Theories of Emergence [PDF]

open access: yes, 2014
“Emergence” – the notion of novel, unpredictable and irreducible properties developing out of complex organisational entities – is itself a complex, multi-dimensional concept.
Tom, Ritchey
core   +2 more sources

Magnetic loop emergence within a granule

open access: yes, 2009
We investigate the temporal evolution of magnetic flux emerging within a granule in the quiet-Sun internetwork at disk center. We combined IR spectropolarimetry performed in two Fe I lines at 1565 nm with speckle-reconstructed G-band imaging.
Balthasar, H.   +6 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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