Results 101 to 110 of about 1,727,958 (299)
The Ontology of Complex Systems: Wimsatt on Emergence
openThis dissertation aims to offer a perspective on Wimsatt's work, emphasizing its originality in addressing ontological issues related to emergence. The first section provides a concise overview of Wilson's concept of Weak Emergence, serving as common
LONGATO, ORSO LODOVICO
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
“Noninvasive predictive marker for esophageal variceal bleeding”
BMC GastroenterologyObjective Esophageal varices are common in cirrhosis with portal hypertension; some patients face high risk of life-threatening esophageal variceal bleeding (EVB).
Shuo Zhang +3 more
doaj +1 more source
Forms of Emergence and the Evolution of Economic Landscapes [PDF]
Over the past two decades, the notion of ÔemergenceÕ has attracted increasing attention and controversy across the social sciences, as par of a growing interest in the applicability of complexity theory to socio-economic-political systems.
Peter Sunley, Ron Martin
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FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
New Approaches to the Circle of Sense and Nonsense
PhilosophiesI will briefly discuss the history of research-related projects that Mark Burgin and I worked on together. I will then discuss our joint research related to the circle of sense and nonsense.
Bill Seaman
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
This large multi-piece installation, entitled Emergence, was exhibited as part of The Figure in Question exhibition at Lake Macquarie City Art ...
Graham Lang (21301700)
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A symbolic model for shape emergence
, 1997 This paper presents a shape representation at the symbolic level that extends the properties of shape in 2D and 3D using the same formalism. This representation is based on the concept of infinite maximal lines and planes. Constraints on their properties
J. Damski, J.S. Gero
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