Results 121 to 130 of about 1,727,958 (299)
Detection of influenza virus in urban wastewater during the season 2022/2023 in Sicily, Italy
Frontiers in Public HealthIntroductionSeasonal influenza generally represents an underestimated public health problem with significant socioeconomic implications. Monitoring and detecting influenza epidemics are important tasks that require integrated strategies. Wastewater-based
Carmelo Massimo Maida +20 more
doaj +1 more source
Norm emergence in tag-based cooperation [PDF]
, 2010 In multi-agent systems norms are an important influence that can engender cooperation by constraining actions and binding groups together. A key question is how to establish a suitable set of norms in a decentralised population of self-interested agents,
Griffiths, N +3 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Three essays on firms' emergence
This research explores firms’ emergence from bankruptcy in the context of firm size, managerial ability, and firm-level political risk. It addresses the key problem of why certain firms that file for Chapter 11 bankruptcy are more vulnerable to collapse ...
Zikri, Miftah
core +1 more source
Nihon Kikai Gakkai ronbunshuRecent regulations on the spring-like effect (SLE) in golf drivers cap the characteristic time (CT) at 239±18 μs, which limits performance gains derived solely from face deflection.
Nobuhisa KATSUMATA +2 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
An analysis of norm emergence in Axelrod's model [PDF]
, 2010 Norms are a valuable mechanism for establishing coherent cooperative behaviour in decentralised systems in which no central authority exists. One of the most influential formulations of norm emergence was proposed by Axelrod, who defined a model of norms
Mahmoud, Samhar +3 more
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