Results 121 to 130 of about 1,791,218 (298)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Seed dormancy and seedling emergence studies in Avena fatua L.
Studies were made of seedling emergence of three phenotypes of Avena fatua L. with different coloured lemmas (fA, fB, fC) originally collected from one site.
N. C. B. PETERS, Peters, N. C. B.
core +1 more source
Commentary: Behavior analysis and behavioral neuroscience
Teresa Camille Kolu
doaj +1 more source
New Approaches to the Circle of Sense and Nonsense
I will briefly discuss the history of research-related projects that Mark Burgin and I worked on together. I will then discuss our joint research related to the circle of sense and nonsense.
Bill Seaman
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
An analysis of norm emergence in Axelrod's model [PDF]
Norms are a valuable mechanism for establishing coherent cooperative behaviour in decentralised systems in which no central authority exists. One of the most influential formulations of norm emergence was proposed by Axelrod, who defined a model of norms
Mahmoud, Samhar +3 more
core
Prevalence and Genetic Diversity of Bat Hepatitis B Viruses in Bat Species Living in Gabon
Hepatitis B virus (HBV) infection leads to around 800,000 deaths yearly and is considered to be a major public health problem worldwide. However, HBV origins remain poorly understood.
Danielle S. Koumba Mavoungou +8 more
doaj +1 more source

