Results 131 to 140 of about 1,408,830 (315)
Solar flux emergence : a three-dimensional numerical study
, 2008 Flux is continually emerging on the Sun, making its way from the solar interior up into the atmosphere. Emergence occurs on small-scales in the quiet Sun where magnetic fragments emerge, interact and cancel and on large-scales in active regions where ...
Murray, Michelle J.
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2019 : The emergence of resistant biotypes of the Amaranthus palmeri species in cotton production areas of the state of Mato Grosso, Brazil, generated the need for correct identification of this species and information on viable herbicidal tools for their ...
P.J. CHRISTOFFOLETI (6675434) +5 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Knowledge and Information SystemsKnowledge and Information Systems (KAIS ...
openaire +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
An overview of the best available research evidence from around the world (i.e., evidence syntheses) and local research evidence (i.e., single studies) and, if applicable, a scan of experiences from other countries and from Canadian provinces and ...
Ali, A +6 more
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
An overview of the best available research evidence from around the world (i.e., evidence syntheses) and local research evidence (i.e., single studies) and, if applicable, a scan of experiences from other countries and from Canadian provinces and ...
Alam, S +10 more
core