Results 91 to 100 of about 1,727,958 (299)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Riding behavior-based HMIs for motorcycle safety (A comparative study of alert and real-time feedback systems)

Journal of Advanced Mechanical Design, Systems, and Manufacturing
Motorcycle assistance systems have been an increasing focus of research in recent years to promote safer riding practices and mitigate motorcycle-related accidents.
Kifle Hailu GEBRETSADIK, Keisuke SUZUKI
doaj   +1 more source

Emergence in organizations: The reflexive turn

, 2010
In this paper we explore the role and meaning of the concept of emergence in the study of organizations. A brief recount of the history of the concept of emergence illustrates a general failure to distinguish between the mechanisms of emergence present ...
Kay, R, Goldspink, C
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Prognostic value of systemic immune-inflammation index in the diagnosis of preeclampsia

Heliyon
Background: Preeclampsia is a serious complication of pregnancy with negative consequences for the mother and fetus. It was aimed to investigate whether the systemic immune inflammation index is a parameter that will facilitate the diagnosis of ...
Mucahit Kapci, Kemal Sener, Adem Cakir, Ertugrul Altug, Ramazan Guven, Akkan Avci   +5 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Update on tick-borne pathogens detection methods within ticks

Current Research in Parasitology and Vector-Borne Diseases
Ticks are known vectors of various pathogens, including bacteria, parasites and viruses, that impact both animal and human health. Improving knowledge of the distribution of tick-borne pathogens, combined with their early detection in ticks, are ...
Eva Krupa, Alexis Dziedziech, Richard Paul, Sarah Bonnet   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Tick exposure biomarkers: A One Health approach to new tick surveillance tools

Current Research in Parasitology and Vector-Borne Diseases
The spread of tick-borne disease (TBD) is escalating globally, driven by climate change and socio-economic shifts, underlining the urgency to improve surveillance, diagnostics, and control strategies.
Alexis Dziedziech, Eva Krupa, Kristina E.M. Persson, Richard Paul, Sarah Bonnet   +4 more
doaj   +1 more source

Emerging Sight, Emerging Blindness

, 2012
This essay covers two main topics: the role of the “double vi-sion” of the sight/nonsight of blinking in selected fiction of Neil Gaiman and China Miéville, and an examination of the role of blindness and sight surrounding “Molyneux’s question.” In Gaiman’s work “double vision” functions as a synchronic representation of diachronic events.
openaire   +1 more source