Results 161 to 170 of about 3,349,217 (305)

Effects of fire timing and snow cover on tallgrass prairie plant re-emergence phenology, growth rate, and flowering. [PDF]

Ecol Appl
Homann MA, Damschen EI.
europepmc   +1 more source

Emerging Infections [PDF]

BMJ, 1998
openaire   +3 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Host jumps need not be common just because spillover is. [PDF]

PLoS Biol
Yuksel M, Mideo N.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Post-pandemic changes in population immunity have reduced the likelihood of emergence of zoonotic coronaviruses. [PDF]

Nat Commun
Imrie RM, Bissett LA, Raveendran S, Manali M, Amat JAR, Mojsiejczuk L, Logan N, Park A, Baguelin M, Viana M, Willett BJ, Murcia PR.   +11 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Mitigation of soil water stress by moderately deep sowing and exogenous application of glucosinolates during the early seedling stage in rapeseed. [PDF]

Front Plant Sci
Bai C, Lei Y, Batool M, El-Badri AM, Chang Y, Kuai J, Wang B, Zhao J, Xu Z, Anwar S, King GJ, Wang J, Zhou G.   +12 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Virus discovery in sandflies, from field studies to phylogenetic tree building: classic methods versus novel methods, what do we need to address public health impact?

Parasites & Vectors, 2014
L Bichaud, C Alkan, G Piorkowski, E Zhioua, I Bitam, A Izri, V Moin Vaziri, B Alten, Y Ozbel, OE Kasap, X De Lamballerie, RN Charrel   +11 more
doaj   +1 more source