Results 61 to 70 of about 1,650,458 (302)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Evaluation of the epidemic intelligence from open sources (EIOS) system for the early detection of outbreaks and health emergencies in the African region

BMC Public Health
Introduction Public health today is challenged by a wide array of hazards that threaten humans, often resulting in high rates of morbidity and mortality when they strike. These events should be detected and responded to as early as possible to save lives
George Sie Williams, Etien Luc Koua, Philip Abdelmalik, Freddy Kambale, Emerencienne Kibangou, Joyce Nguna, Charles Okot, Godwin Akpan, Fleury Moussana, Jean Paul Kimenyi, Ramazani Zaza, Raquel Medialdea Carerra, Yasmin Rabiyan, Mark Woolhouse, Joseph Okeibunor, Abdou Salam Gueye   +15 more
doaj   +1 more source

Variability in the inorganic composition of colored acrylonitrile–butadiene–styrene and polylactic acid filaments used in 3D printing

SN Applied Sciences, 2022
Fused filament fabrication is a 3D printing technique that has gained widespread use from homes to schools to workplaces. Thermoplastic filaments, such as acrylonitrile–butadiene–styrene (ABS) and polylactic acid (PLA), are extruded at temperatures near ...
Derek M. Peloquin, Logan N. Rand, Eric J. Baumann, Ali Gitipour, Joanna Matheson, Todd P. Luxton   +5 more
doaj   +1 more source

The Role of Transportation in Campus Emergency Planning, MTI Report 08-06 [PDF]

, 2009
In 2005, Hurricane Katrina created the greatest natural disaster in American history. The states of Louisiana, Mississippi and Alabama sustained significant damage, including 31 colleges and universities.
Edwards, Frances, Goodrich, Daniel C.
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Handbook of Emergency Management For State-Level Transportation Agencies, MTI Report 09-10 [PDF]

, 2010
The Department of Homeland Security has mandated specific systems and techniques for the management of emergencies in the United States, including the Incident Command System, the National Incident Management System, Emergency Operations Plans, Emergency
Edwards, Frances L., Goodrich, Daniel C.
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Effects of tropical cyclone Freddy on the social determinants of health: the narrative review of the experience in Malawi

BMJ Public Health
Malawi—one of the low-income countries in Africa—has witnessed a series of flood-related disasters in many years. The recent tropical cyclone Freddy (TCF) has indispensable effects on the unequal distribution of the social determinants of health with ...
Joseph Okeibunor, Otim Patrick Cossy Ramadan, Ishata Nannie Conteh, Abdou Salam Gueye, Jayne Byakika-Tusiime, Annie Chauma-Mwale, Ebenezer Obi Daniel, Dick Chamla, Fiona Braka, Neema Kimambo Rusibamayila, Chol Thabo Yur, Emmanuel Maurice Ochien, Mathew Kagoli   +12 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source