Results 41 to 50 of about 5,537,365 (298)

The effect of shoulder muscle succinylcholine injection on the foreleg raising power: Sion's local paralysis

Heliyon, 2023
Objective: We examined the change in foreleg raising power after Sion's local paralysis (SLP) with succinylcholine in the shoulder muscle. Methods: A randomized, double blind, placebo-controlled, porcine study was designed and performed at a research ...
Sion Jo, Yu Chan Kye, Jungyoup Lee, Euigi Jung, Minwoo Kang, Byunghyun Kim, Dongsung Kim, Boyoung Park   +7 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

An analysis of ambulance re-contacts after non-conveyance: a retrospective cohort study in the Netherlands

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Background Non-conveyance is an increasing part of ambulance care and has to be safe. One of the indicators to measure safety is an ambulance re-contact within 72 h. However, solely measuring the percentage of re-contacts has limited validity as it lacks
Susanne E. de Loor, Tessa Verheij, Thomas Karol, Franciscus G. M. H. M. Cuppen, Frits van Dijk, Femke Goldstein, Joyce Janssen, Remco H. A. Ebben   +7 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Demand analysis and tactical deployment of ambulance services in the National Ambulance Service Midlands Region [PDF]

, 2010
This project was funded by the Pre-Hospital Emergency Care Council and co-ordinated by Dr Geoff King of the Pre-Hospital Emergency Care Council and Mr Frank McClintock Assistant National Director, National Hospital’s Office.
Pre-Hospital Emergency Care Council (PHECC)
core  

Relaxation and strain among emergency medical service personnel and emergency control center dispatchers during the first two waves of the SARS-CoV-2 pandemic

Medycyna Pracy, 2023
Background Workloads of emergency medical service personnel (EMP) and emergency control center dispatchers (CCDs) were manifold. The SARS-CoV-2 pandemic presented new challenges for the prehospital emergency medical service. The purpose of this study was
Heiko Schumann, Irina Böckelmann, Beatrice Thielmann   +2 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Using handheld pocket computers in a wireless telemedicine system [PDF]

, 2006
Objectives: To see if senior emergency nurse practitioners can provide support to inexperienced ones in a Minor Injuries Unit by using a wireless LAN system of telemedicine transmitting images to a PDA when they were on duty. In addition, whether such
Tachakra, S, Tachakra, F, Banitsas, K, Solomon, H, Corrigan, R, Song, Y   +5 more
core   +1 more source

Unconditional Care in Academic Emergency Departments [PDF]

, 2020
Recent news stories have explicitly stated that patients with symptoms of COVID-19 were "turned away" from emergency departments. This commentary addresses these serious allegations, with an attempt to provide the perspective of academic emergency ...
Burton, John H, Miner, James R, Ian B.K. Martin, Lall, Michelle D, Newgard, Craig D., Coates, Wendy C, Angela M. Mills, Bird, Steven B., Mills, Angela M, Newgard, Craig D, John H. Burton, Dorner, Stephen C., Kaji, Amy H., Holmes, James F, Michelle D. Lall, Holmes, James F., Kaji, Amy H, Martin, Ian BK, Burton, John H., Kline, Jeffrey A, Megan L. Ranney, Dorner, Stephen C, Richard E. Wolfe, Steven B. Bird, Quest, Tammie, Stephen C. Dorner, Amy H. Kaji, Mills, Angela M., Ranney, Megan L, Zachary F. Meisel, Craig D. Newgard, Meisel, Zachary F, Coates, Wendy C., Wolfe, Richard E, Wendy C. Coates, Meisel, Zachary F., Christopher R. Carpenter, Miner, James R., Jeffrey A. Kline, James R. Miner, Martin, Ian B. K., Lall, Michelle D., Bird, Steven B, Carpenter, Christopher R., James F. Holmes, Kline, Jeffrey A., Ranney, Megan L., Carpenter, Christopher R, Tammie Quest, Wolfe, Richard E.   +49 more
core   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source