Results 61 to 70 of about 5,537,365 (298)

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus, Devin L. Brown, Bernadette Boden‐Albala   +2 more
wiley   +1 more source

Use of Self-Efficacy Scale in Mass Casualty Incidents During Drill Exercises

BMC Health Services Research
Introduction Medical First Responders (MFRs) in the emergency department SUMMA 112 are tasked with handling the initial management of Mass Casualty Incidents (MCI) and building response capabilities.
María Carmen Cardós-Alonso, Miguel Inzunza, Lina Gyllencreutz, Salvador Espinosa, Tatiana Vázquez, Maria Aranzazu Fernandez, Alberto Blanco, Ana María Cintora-Sanz   +7 more
doaj   +1 more source

Outcome, quality of life and direct costs after out-of-hospital cardiac arrest in an urban region of Switzerland

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2019
Background Considering the significant morbidity and mortality of out-of-hospital cardiac arrest, only little data on survival or quality of life after successful resuscitation is available in Europe.
Raphael Ruch, Laura Stoessel, Philipp Stein, Michael Thomas Ganter, Daniel Anthony Button   +4 more
doaj   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

The CoolCot trial: active methods of therapeutic hypothermia for newborns with hypoxic ischaemic encephalopathy (HIE) during neonatal transport: a study protocol for a randomised controlled trial comparing battery-enabled servo-controlled cooling blankets and ice-gel pack methods

Trials
Background Impaired oxygen delivery or blood flow to the brain around the time of birth can cause injury. Hypoxic ischaemic encephalopathy (HIE) is a leading cause of death and disability in term and near-term infants.
Adam Heathcote, Kate Hooper, Matt Cooper, Sebastian Lee, Fan Tang, Vamsi Batta, Saumil Desai, Jacqueline Gardiner, Alex Wilson, Kylie McDonald, Alysha Timoney, Tess Watson, Jonathan Davis   +12 more
doaj   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

ESTIMATING THE BENEFITS OF REGIONALIZING EMERGENCY MEDICAL SERVICE PROVISION [PDF]

Local area governments have experienced increasingly stringent budget constraints in recent years. Innovations in service delivery provide one avenue for increasing the effectiveness of resource allocations.
Wilson, James M., Dudek, Daniel J.
core  

Journal of Emergency Medicine [PDF]

, 2019
Having an advisor offers medical students many advantages, including increased likelihood of matching into their top choices. Interestingly, students who choose emergency medicine (EM) as a specialty are more likely to seek advising. However, finding and
Kazzi, Amin Antoine Nabih, Haydel, Micelle J., Blumstein, Howard, Keller, Barbara L., Epter, Michael L., Blumstein, Howard A., Hopson, Laura, Lareau, Stephanie, Hitti, Eveline A., Epter, Michael, Hopson, Laura R., Cheaito, Mohamad Ali, Kazzi, Amin, Lareau, Stephanie A.   +13 more
core   +1 more source

The impact of additional special emergency medical service units on non-traumatic adult out-of-hospital cardiac arrest outcomes in a high-resource metropolitan area

Resuscitation Plus
Background: Out-of-hospital cardiac arrest (OHCA) requires an effective cardiopulmonary resuscitation (CPR) and emergency medical service (EMS) response, yet survival rates remain low at 8.0–11.3 %.
Andrea Kornfehl, Mario Krammel, Daniel Grassmann, Maximilian de Zordo, Roman Brock, Christoph Veigl, Rene Adler, Sabine Dunkl, Mathias Gatterbauer, Philipp Gonzo, Bertram Schadler, Patrick Aigner, Michael Girsa, Patrick Glaninger, Andreas Zajicek, Patrick Sulzgruber, Thomas Uray, Sebastian Schnaubelt   +17 more
doaj   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source