Results 41 to 50 of about 133,089 (241)

Design’s Ontology: Emergent Properties and Affordance

Eidos. A Journal for Philosophy of Culture
This essay proposes a visualist ontological framework for understanding design, rooted fundamentally in the theories of emergent properties and affordances. Opposing functionalist and intentionalist paradigms, the framework underscores design’s visuality
Michalle Gal
doaj   +1 more source

How the engineering of Swarming Behaviors could be drawing on Social Sciences [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Emergent behavior in swarming and self-organizing systems can be systematically studied. This paper proposes to draw on excisting conceptual frameworks from the social sciences to do so.
H. Hildmann, H. Hildmann, R. Nockerts, S. Coffeng, H. Karvonen, J. van der Heuvel, R. van der Pluijm, F. Saffre   +7 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Revealing the structural evolution of CuAg composites during electrochemical carbon monoxide reduction

Nature Communications
Comprehending the catalyst structural evolution during the electrocatalytic process is crucial for establishing robust structure/performance correlations for future catalysts design.
Di Wang, Hyun Dong Jung, Shikai Liu, Jiayi Chen, Haozhou Yang, Qian He, Shibo Xi, Seoin Back, Lei Wang   +8 more
doaj   +1 more source

Emerging Design Processes for Emerging Technologies [PDF]

Proceedings of the 1st International Conference on Progress in Additive Manufacturing, 2014
Additive Manufacturing Technology (AMT) is expected to have a deep impact on the way we both produce and consume products in the future. Its technical benefits are well documented, but how it will influence the design process is less clear. This paper will deal with the influence AM technology has had on design processes, and also introduce some ...
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Designing in the Times of AI: Co-Creation as a Strategy Towards Emergent Learning Design

African Journal of Inter-Multidisciplinary Studies
This paper explores co-creation as a strategy for emergent learning design in developing a new postgraduate diploma in blended and online learning (BOLD) at a large South African university. In this conceptual paper, grounded both in theory and critical
Daniela Gachago, Cheng-Wen Huang, Christine Immenga, Glenda Cox, Tefo Mosienyane, Shanali Govender   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source