Results 51 to 60 of about 933 (281)

Psycho-physiologic emergentism; four minds in a body

open access: yesJournal of Mind and Medical Sciences, 2017
The mind-body problem represents one of the most debated topics in the neurosciences. From a psychological standpoint, abstract/non-material data are an intrinsic part of the mind, intervening to a large extent in reasoning and decision making processes.
David L. Rowland, Ion G. Motofei
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

BRAIN Journal - The Differences between Emergentism & Skill Acquisition Theory

open access: yes, 2016
Although both emergentism and skill acquisition theory developed in the same field (cognitive theories) and as an attempt to replace Universal grammar-based approaches, there are some differences between these two theories.
Naeemeh Kharaghani
core   +1 more source

Idea emergencji – zarys ogólny

open access: yesZagadnienia Filozoficzne w Nauce, 2013
This article has an introductory character and systematizes the topic. It introduces the idea of emergence which is currently enjoying something of a renaissance and aims to bring order to the terminology associated with this idea.
Tomasz Maziarka
doaj  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

CREATED FOR EVERLASTING LIFE: CAN THEISTIC EVOLUTION PROVIDE AN ADEQUATE CHRISTIAN ACCOUNT OF HUMAN NATURE?

open access: yesZygon, 2013
Christians who affirm standard science and the biblical doctrine of creation often endorse theistic evolution as the best approach to human origins. But theistic evolution is ambiguous. Some versions are naturalistic (NTE)—God created humans entirely by
doaj   +2 more sources

Looking for Emergence in Physics

open access: yesPhenomenology and Mind, 2017
Despite its recent popularity, Emergence is still a field where philosophers and physicists often talk past each other. In fact, while philosophical discussions focus mostly on ontological emergence, physical theory is inherently limited to the ...
Joana Rigato
doaj   +1 more source

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