Results 71 to 80 of about 933 (281)
Arcos DesignEste estudo analisa o papel do Design Emergente, com foco em três dissertações de um Programa de Pós-graduação em Design, cada uma dedicada a um contexto específico: urbano, rural e empresarial/tecnológico. Destaca-se o cruzamento entre os trabalhos, evidenciando como o Design pode promover dispositivos considerando não apenas as necessidades humanas ...
Adson Pinheiro Queiroz Viana +4 more
openaire +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Weak Emergentism and Social Systems
, 2016 An emergent higher-level property is ‘nonvacuously weak’ if it is specified both in terms of the manifest and latent powers of its constituents. The manifest powers are always in action, while the latent ones are activated only when lower-level entities ...
MASCELLA, RAFFAELE, Raffaele Mascella
core +1 more source
Emergentism in sociology : epistemological brigde between action and structure
, 2023 Jedna od glavnih diskrepancija sociologije kao znanosti je upravo rascjep između mikro i makropristupa istraživanja. Iz te diskrepancije rodila su se dva suprotstavljena pristupa proučavanja društvene zbilje: strukturalizam i teorije akcije. Ideja mojega
Haček, Vilim
core +2 more sources
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
«Land of Confusion»: Quantum Physic In IR Theory?
Vestnik MGIMO-Universiteta, 2016 The article deals with the "Quantum mind"hypothesis which has been elaborated in recent works of Alexander Wendt. It is ultimately significant to analyze this hypothesis and to expand on its difficulties and possible inconsistencies given Wendt's ...
Tatiana A. Alekseeva +2 more
doaj +2 more sources
Scientia et Fides, 2016 One of the main challenges of the nonreductionist approach to complex structures and phenomena in philosophy of biology is its defense of the plausibility of the theory of emergence and downward causation.
Mariusz Tabaczek
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Explanation, Prediction, and Reduction in Emergentism
, 1997 The core doctrine of emergentism is that among the properties of a complex system are those that are neither predictable nor explainable in terms of the properties of the lower-level constituents or subsystems from which they emerge.
Kim, Jaegwon
core +1 more source