Results 81 to 90 of about 933 (281)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

PANPSYCHISM, EMERGENTISM AND THE MIND-BODY PROBLEM

open access: yes
Can panpsychism really represent a solution to the mind-body problem? Does a dualist position on this issue make sense today? A comparison will be made, in this work, between the physicalist emergentism and the panpsychism, which is today widely studied,
Gaetano Licata
core   +1 more source

The foundational crisis of cognitive science: challenging the emergentist challenge

open access: yesRevista de Filosofia, 2010
The following pages contend that, in spite of its intensive development, contemporary cognitive science has recently entered a phase of fairly acute uncertainty and confusion regarding some of its most essential foundations. They emphasize two aspects of
Jean-Michel Roy
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Revitalization of Emergentism in SLA: A Panacea!

open access: yes, 2012
Emergentists claim learning takes place by extracting regularities from the input. By the same token, Ellis (1998) disputed the view held by generative linguistics that such a complex phenomenon as language can only be learnt if it is assumed that humans
Shakouri Masouleh, Nima
core   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

Organicism and Reductionism in Cancer Research: Towards a Systemic Approach [PDF]

open access: yes, 2007
In recent cancer research, strong and apparently conflicting epistemological stances have been advocated by different research teams in a mist of an ever-growing body of knowledge ignited by ever-more perplexing and non-conclusive experimental facts: in ...
Malaterre, Christophe   +1 more
core   +1 more source

Enfermedades emergentes y re-emergentes

open access: yesRevista de la Facultad de Medicina, 1996
Ante el surgimiento del Virus de la Inmunodeficiencia Humana, HIV, del Síndrome de la Inmuno Deficiencia Adquirida, SIDA, y del mortal virus del Ebola, que azotó al Zaire durante el año de 1995, el Instituto de Medicina de los Estados Unidos de América constituyo el Comité de Amenazas Microbianas Emergentes para la Salud, conformado por especialistas ...
openaire   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Mental Causation and Intelligibility

open access: yesHumana.Mente: Journal of Philosophical Studies, 2015
I look at some central positions in the mental causation debate – reductionism, emergentism, and nonreductive physicalism – on the hypothesis that mental causation is intelligible.
David Robb
doaj  

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