FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Philosophy and neuroscience on consciousness - response to Felipe León and Dan Zahavi. [PDF]
Acta Neurochir (Wien), 2023 Wagner-Altendorf TA.
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Christianity and Religious Naturalism
St Andrews Encyclopaedia of TheologyThis article provides an overview of contemporary religious naturalism, with a specific focus on Christian articulations of this emerging worldview and movement.
Mikael Leidenhag
doaj
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Ciencia, bioquímica y panteísmo en Arthur Peacocke
Pensamiento. Revista de Investigación e Información Filosófica, 2016 Este artículo presenta y discute el corpus de doctrina elaborada por Arthur Peacocke sobre la idea de Dios, y de lo teológico-cristiano, que debe ser hoy construida desde la imagen científica del mundo, especialmente la imagen científica de la vida, la ...
Javier Monserrat
doaj
Studying second language acquisition in the age of large language models: Unlocking the mysteries of language and learning, A commentary on "Age effects in second language acquisition: Expanding the emergentist account" by Catherine L. Caldwell-Harris and Brian MacWhinney. [PDF]
Brain Lang, 2023 Marian V.
europepmc +1 more source
, 2012 La arquitectura escarpa su perfil en busca de nuevas soluciones. Madrid y Teruel inauguran estos días nuevos ejemplos de intervenciones en las que el terreno es protagonista. Conviene preguntarse si estas geologías artificiales, más que un llamativo recurso formal, no serán por fin auténticas construcciones públicas, nuevos espacios emergentes.
Esteban Maluenda, Inmaculada +1 more
openaire +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source