Results 91 to 100 of about 1,561,128 (291)

microRNA. Diagnostic Perspective [PDF]

open access: yes, 2015
Biomarkers are biological measures of a biological state. An ideal marker should be safe and easy to measure, cost efficient, modifiable with treatment, and consistent across gender and ethnic groups. To date, none of the available biomarkers satisfy all
FARUQ, MD OMAR, VECCHIONE, ANDREA
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Depression, anxiety, and stress among mothers of children with thalassemia in Bangladesh: a cross-sectional study

open access: yesBMC Women's Health
Background Despite Bangladesh being one of the major hotspots of thalassemia in the world, this preventable inherited blood disorder is neglected in research and policy level.
Farhin Islam   +5 more
doaj   +1 more source

Approche intégrée des maladies émergentes à transmission vectorielle et changements mondiaux : exemple et perspective [PDF]

open access: yes, 2009
Vector-borne diseases (e.g., bluetongue or Rift Valley fever) are very sensitive to environmental changes. As such, they are excellent models to study disease emergence in a changing world, with more intense commercial exchanges, climate changes, and ...
Aumont, Gilles   +3 more
core  

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

SARS Another Emerging Disease [PDF]

open access: yesDental Update, 2003
Severe acute respiratory syndrome, SARS, is an illness that has been recently reported in Asia, North America, Europe and Africa. SARS appears to be a new disease. The first known case of atypical pneumonia occurred on 16 November 2002 in Foshan City, Guangdong Province, China. However, its significance was not known until later.
openaire   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Detection of Ehrlichia ruminantium infection in cattle in Cameroon

open access: yesBMC Research Notes, 2018
Objectives Ehrlichia ruminantium infection (heartwater) is a major constraint that impacts negatively on the cattle industry development in sub-Saharan Africa and so far, little is known of the presence of heartwater in cattle in Cameroon.
Seraphine N. Esemu   +2 more
doaj   +1 more source

Metagenomic characterisation of additional and novel avian viruses from Australian wild ducks

open access: yesScientific Reports, 2020
Birds, notably wild ducks, are reservoirs of pathogenic and zoonotic viruses such as influenza viruses and coronaviruses. In the current study, we used metagenomics to detect and characterise avian DNA and RNA viruses from wild Pacific black ducks ...
Jessy Vibin   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

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