Results 111 to 120 of about 822,085 (315)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Vaccines for biodefense and emerging and neglected diseases /

open access: yes, 2009
The last 20 years has seen a rapid increase in infectious diseases, particularly those that are termed "emerging diseases" such as SARS, "neglected diseases" such as malaria and those that are deemed biothreats such as anthrax. It is well-recognized that
Barrett, A. D. T.(Alan D. T.)   +1 more
core  

Distinct functional connectivity patterns in myalgic encephalomyelitis and long COVID patients during cognitive fatigue: a 7 Tesla task-fMRI study

open access: yesJournal of Translational Medicine
Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and long COVID are chronic debilitating illnesses featuring fatigue, post-exertional malaise (PEM) and neurocognitive deficits.
Maira Inderyas   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

National Center for Emerging and Zoonotic Infectious Diseases: Protecting Health at Home & Abroad [PDF]

open access: yes
CDC\u2019s National Center for Emerging and Zoonotic Infectious Diseases (NCEZID) protects people in the United States and around the globe from emerging (new) and zoonotic (spread between people and animals) infectious diseases.

core  

Emerging and Re-Emerging Diseases Caused by Badnaviruses. [PDF]

open access: yesPathogens, 2023
Ishwara Bhat A   +2 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Emerging infectious diseases : 2017 journal report [PDF]

open access: yes
In the 25 years since the Institute of Medicine issued its landmark report on Emerging Infections: Microbial Threats to Health in the United States, much has been accomplished and far-reaching recommendations have been issued.

core  

Impaired brain intrinsic connectivity in long COVID during cognitive exertion revealed by independent component analysis

open access: yesScientific Reports
Cognitive dysfunction is a symptom of Long COVID. To characterize functional connectivity changes that may contribute to cognitive dysfunction in Long COVID (LCov), two consecutive 450 s functional magnetic resonance imaging (fMRI) scans (Runs 1 and 2 ...
Leighton Barnden   +5 more
doaj   +1 more source

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