Results 81 to 90 of about 1,561,128 (291)

Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2

mBio, 2020
To date, limited genetic changes in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome have been described. Here, we report a 382-nucleotide (nt) deletion in SARS-CoV-2 that truncates open reading frame 7b (ORF7b) and ORF8, removing ...
Yvonne C. F. Su, Danielle E. Anderson, Barnaby E. Young, Martin Linster, Feng Zhu, Jayanthi Jayakumar, Yan Zhuang, Shirin Kalimuddin, Jenny G. H. Low, Chee Wah Tan, Wan Ni Chia, Tze Minn Mak, Sophie Octavia, Jean-Marc Chavatte, Raphael T. C. Lee, Surinder Pada, Seow Yen Tan, Louisa Sun, Gabriel Z. Yan, Sebastian Maurer-Stroh, Ian H. Mendenhall, Yee-Sin Leo, David Chien Lye, Lin-Fa Wang, Gavin J. D. Smith   +24 more
doaj   +1 more source

Social research on neglected diseases of poverty: Continuing and emerging themes [PDF]

, 2009
Copyright: © 2009 Manderson et al.Neglected tropical diseases (NTDs) exist and persist for social and economic reasons that enable the vectors and pathogens to take advantage of changes in the behavioral and physical environment.
A Danso-Appiah, A Utarini, AC Crampin, B Pond, BD Paul, BV Babu, C Braga, C Kendall, C Kendall, C Lengeler, C Lengeler, C Lengeler, C Lengeler, C Vlassoff, C Vlassoff, C Vlassoff, C Vlassoff, C Vlassoff, C Vlassoff, CA Possas, CM Morel, CM Morel, DA Macer, DA Walton, DH Molyneux, DM Saladiakanda, E Blas, EM Rathgeber, F Espino, G Mubyazi, G Yamey, GM Foster, H Campbell, H Lubell, H Zar, IA Agyepong, IA Agyepong, Irene Agyepong, J Coreil, J Lines, J Pepin, J Sommerfeld, J Utzinger, JD Njau, JDH Porter, Jens Aagaard-Hansen, JF Kengeyakayondo, JH Richardus, Johannes Sommerfeld, KD Ramaiah, KT Silva, L Clemmons, L Manderson, L Pauwels, L Saker, Lenore Manderson, LM Whiteford, Margaret Gyapong, ML Heijnders, MR Bhatia, N Kikumbih, N Marshall, P Allotey, P Allotey, P Hunt, P Hunt, P Vanamail, Pascale Allotey, PJ Hotez, PL Rosenfield, PL Rosenfield, S Fonn, S Fonn, S Fonn, S Gove, S Khun, S Khun, S Rao, S Theobald, SH Arahman, SP Zodpey, VV Valla, W Onyango-Ouma   +82 more
core   +4 more sources

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Emerging Challenges and Opportunities in Infectious Disease Epidemiology. [PDF]

, 2019
Much of the intellectual tradition of modern epidemiology stems from efforts to understand and combat chronic diseases persisting through the 20th century epidemiologic transition of countries such as the United States and United Kingdom.
Lewnard, Joseph A, Reingold, Arthur L
core  

Chronic diseases: the emerging pandemic. [PDF]

, 2011
According to the 2011 World Health Organization Global Status Report, of the 57 million annual global deaths – a staggering 36 million or over 63% are due to chronic diseases.1 Four noncommunicable diseases - namely cardiovascular, cancer, diabetes, and ...
Terzic, Andre, Waldman, Scott A.
core   +2 more sources

Emerging Ferret Diseases

Journal of Exotic Pet Medicine, 2010
There are a number of newly described and emerging disease syndromes affecting the domestic ferret, and the purpose of this article is to make veterinarians aware of these diseases. A recently described systemic coronavirus infection appears to be a variant of the ferret enteric coronavirus and is currently termed "ferret infectious peritonitis ...
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Health-related quality of life in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Post COVID-19 Condition: a systematic review

Journal of Translational Medicine
Purpose Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Post COVID-19 Condition (PCC) are debilitating, chronic multi-systemic illnesses that require multidisciplinary care.
Breanna Weigel, Maira Inderyas, Natalie Eaton-Fitch, Kiran Thapaliya, Sonya Marshall-Gradisnik   +4 more
doaj   +1 more source

Integrated Serologic Surveillance of Population Immunity and Disease Transmission. [PDF]

, 2018
Antibodies are unique among biomarkers in their ability to identify persons with protective immunity to vaccine-preventable diseases and to measure past exposure to diverse pathogens. Most infectious disease surveillance maintains a single-disease focus,
Arnold, Benjamin F, Lammie, Patrick J, Priest, Jeffrey W, Scobie, Heather M   +3 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source