Results 81 to 90 of about 7,314,464 (305)

Effectiveness of sensorimotor training in different social conditions of men’s and women’s activities in mono-gender dyads

RUDN Journal of Medicine
Relevance. Investigation the features of human achievement of the results of purposeful activity in different conditions of social interactions is relevant and of high significance.
Elena P. Murtazina, Ekaterina S. Galushka, Olga I. Ermakova, Oksana M. Zotova, Maria. A. Markovtseva, Natalia Yu. Trifonova, Sergey S. Pertsov   +6 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Emerging Technologies for Emerging Markets [PDF]

, 2015
This book introduces inclusive-cost-effective (ICE) approaches that have the potential to transform all aspects of daily lives of people at the base of the pyramid in the economic scale, who represent more than 75% of the world population. ICE means that the approaches must meet the affordability level at the base of the pyramid.
Vong, John, Song, Insu
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Technical Change Theory and Learning Curves: Patterns of Progress in Energy Technologies [PDF]

, 2006
This paper presents a comparative analysis of energy technology learning and progress within the framework of Schumpeter’s invention-innovation-diffusion paradigm.

core   +2 more sources

Codon-optimization in gene therapy: promises, prospects and challenges

Frontiers in Bioengineering and Biotechnology
Codon optimization has evolved to enhance protein expression efficiency by exploiting the genetic code’s redundancy, allowing for multiple codon options for a single amino acid. Initially observed in E. coli, optimal codon usage correlates with high gene
Anastasiia Iu Paremskaia, Anna A. Kogan, Anastasiia Murashkina, Daria A. Naumova, Anakha Satish, Ivan S. Abramov, Ivan S. Abramov, Sofya G. Feoktistova, Olga N. Mityaeva, Andrei A. Deviatkin, Pavel Yu Volchkov, Pavel Yu Volchkov   +11 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Emerging Technologies Law (Vol. 1-2)

, 2015
This two volume book introduces law and non-law students to emerging technologies, and how law and policy frame our interactions with it both domestically and globally.
Sutton, Victoria
core  

Emerging Technologies towards Energy- Efficient Built Environment Future in Egypt

, 2020
–Building’s sector is one of the major parts of the built environment, influencing most of the people’s day-to-day life factors, it is responsible for 40% and 30% of global energy used and the annual greenhouse gas emissions, respectively.
Abouaiana Ahmed
core