Results 71 to 80 of about 7,314,464 (305)

An ethical framework for emerging technologies: the TEAeM approach [PDF]

open access: yes
The inherent nature of uncertainty and the indefinite time horizon of emerging technologies means that their effective ethical governance is not sufficiently addressed by industry and hence society.
Brooks, L.   +7 more
core   +1 more source

Effect of cyclo-L-prolylglycine on pain response thresholds and morphine-induced analgesia in inbred BALB/c and C57Bl/6 mice

open access: yesФармакокинетика и Фармакодинамика
Relevance. Cyclo-L-prolylglycine (CPG), discovered as an endogenous compound in the central nervous system, is involved in the formation of a reaction to emotional stress in rodents with a pronounced fear reaction and has an analgesic effect in vivo ...
A. V. Nadorova   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

From Committees of RUSA: Best Free Reference Websites Seventeenth Annual List

open access: yes, 2015
Welcome to the seventeenth annual “Best Free Reference Websites” list. It is hard to believe that this project has been around since the late 1990’s.
(ETS), Emerging Technologies Section
core   +1 more source

Future CCS Technologies : European Zero Emission Technology and Innovation Platform [PDF]

open access: yes, 2017
ZEP has published a report entitled "Future CCS Technologies". The report has been developed following COP21 and the aim of limiting the global temperature increase to well below 2°C.
Network Technology – Future CCS Technologies Temporary Working Group
core   +3 more sources

A study on the mnemotropic and antidepressant-like effects of the low-molecular-weight mimetic of nerve growth factor, dipeptide GK-2, in experimental ischemic stroke

open access: yesФармакокинетика и Фармакодинамика
Relevance. The nerve growth factor (NGF), possessing neuroprotective and neuroregenerative properties, holds promise for the development of medications for the treatment of post-stroke conditions. At the Federal Research Center for Innovator and Emerging
P. Yu. Povarnina   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Subtyping Influenza A Viruses: Genomic Perspectives on Taxonomy

open access: yesInternational Journal of Infectious Diseases
Introduction: Influenza A viruses (IAVs) are pathogens found in natural reservoirs. These viruses are able to cross species barriers, which can lead to disease outbreaks in humans.
Dr Andrei Deviatkin   +3 more
doaj   +1 more source

Wetting transitions in droplet drying on soft materials

open access: yesNature Communications, 2019
It has been shown previously that substrate viscoelasticity affects surface wettability. Here the authors observe a wetting transition during drying of droplets on such substrates and elucidate it with high resolution force field measurements thereby ...
Julia Gerber   +4 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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