Results 71 to 80 of about 1,792,929 (311)

Effect of cyclo-L-prolylglycine on pain response thresholds and morphine-induced analgesia in inbred BALB/c and C57Bl/6 mice

Фармакокинетика и Фармакодинамика
Relevance. Cyclo-L-prolylglycine (CPG), discovered as an endogenous compound in the central nervous system, is involved in the formation of a reaction to emotional stress in rodents with a pronounced fear reaction and has an analgesic effect in vivo ...
A. V. Nadorova, K. N. Koliasnikova, I. V. Chernyakova, L. G. Kolik   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A study on the mnemotropic and antidepressant-like effects of the low-molecular-weight mimetic of nerve growth factor, dipeptide GK-2, in experimental ischemic stroke

Фармакокинетика и Фармакодинамика
Relevance. The nerve growth factor (NGF), possessing neuroprotective and neuroregenerative properties, holds promise for the development of medications for the treatment of post-stroke conditions. At the Federal Research Center for Innovator and Emerging
P. Yu. Povarnina, N. M. Sazonova, D. M. Nikiforov, T. A. Gudasheva, V. L. Dorofeev   +4 more
doaj   +1 more source

Nanoprinting organic molecules at the quantum level

Nature Communications, 2019
Integration of emitters for nanophotonic applications requires precise control over their position and orientation. Here, Hail et al. demonstrate the positioning of a single and a small number of oriented molecules with subwavelength accuracy bu direct ...
Claudio U. Hail, Christian Höller, Korenobu Matsuzaki, Patrik Rohner, Jan Renger, Vahid Sandoghdar, Dimos Poulikakos, Hadi Eghlidi   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Remotely hosted services and 'cloud computing' [PDF]

, 2010
Emerging technologies for learning report - Article exploring potential of cloud computing to address educational ...
Cliff, Dave
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Subtyping Influenza A Viruses: Genomic Perspectives on Taxonomy

International Journal of Infectious Diseases
Introduction: Influenza A viruses (IAVs) are pathogens found in natural reservoirs. These viruses are able to cross species barriers, which can lead to disease outbreaks in humans.
Dr Andrei Deviatkin, Miss Sofya Feoktistova, Mr Egor Degtyarev, Dr Pavel Volchkov   +3 more
doaj   +1 more source

POLICY CONSIDERATIONS OF EMERGING INFORMATION TECHNOLOGIES [PDF]

Research and Development/Tech Change/Emerging Technologies,
Sporleder, Thomas L.
core   +1 more source

Emerging Technologies for Emerging Markets [PDF]

, 2015
This book introduces inclusive-cost-effective (ICE) approaches that have the potential to transform all aspects of daily lives of people at the base of the pyramid in the economic scale, who represent more than 75% of the world population. ICE means that the approaches must meet the affordability level at the base of the pyramid.
Vong, John, Song, Insu
openaire   +2 more sources