Results 51 to 60 of about 7,314,464 (305)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Biosensors: Fundamentals, emerging technologies, and applications

, 1996
Biosensors: Fundamentals, Emerging Technologies, and Applications provides insight into the sensing applications of different types of biosensors relating to environmental pollutants, microbiological analysis, and healthcare.
Uslu B., Sezgintürk M.K., Güven, Erdinç, Özkan S.A.   +3 more
core   +1 more source

Germanium disulfide as an alternative high refractive index and transparent material for UV-visible nanophotonics

Light: Science & Applications
Thanks to their record high refractive index and giant optical anisotropy, van der Waals (vdW) materials have accelerated the development of nanophotonics.
Aleksandr S. Slavich, Georgy A. Ermolaev, Ilya A. Zavidovskiy, Dmitriy V. Grudinin, Konstantin V. Kravtsov, Mikhail K. Tatmyshevskiy, Mikhail S. Mironov, Adilet N. Toksumakov, Gleb I. Tselikov, Ilia M. Fradkin, Kirill V. Voronin, Maksim R. Povolotskiy, Olga G. Matveeva, Alexander V. Syuy, Dmitry I. Yakubovsky, Dmitry M. Tsymbarenko, Ivan Kruglov, Davit A. Ghazaryan, Sergey M. Novikov, Andrey A. Vyshnevyy, Aleksey V. Arsenin, Valentyn S. Volkov, Kostya S. Novoselov   +22 more
doaj   +1 more source

Pharmacokinetics of a potential antiepileptic drug GIZh-298

Фармакокинетика и Фармакодинамика
GIZh-298 pharmacokinetics was studied in rats after different dosage regimens.The aim of this study was to study GIZh-298 pharmacokinetics after its multiple intragastric administration.Methods. The study was conducted on outbred male rats.
G. B. Kolyvanov, A. A. Litvin, O. Yu. Kravtsova, O. G. Gribakina, V. P. Zherdev   +4 more
doaj   +1 more source

Carbon-Nanotube Based Thermoelectrical Paste for Enhancing Solar Cell Effciency

E3S Web of Conferences, 2018
A super-passive cooling technique based on a thermal paste is proposed for PV efficiency enhancement in elevated temperature conditions. A mixture between carbon nanotubes and graphene having a promising Seebeck coefficient is chosen.
Mohamed Fathi Sanad, Ahmed Shaker, Sameh O. Abdellatif, Iman Elmahallawi, Hani A. Ghali, Khaled Kirah   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Public Governance and Emerging Technologies

This open access book focuses on public governance’s increasing reliance on emerging digital technologies. ‘Disruptive’ or ‘emerging’ digital technologies, such as artificial intelligence and blockchain, are often portrayed as highly promising, with the ...

core   +1 more source

Exploring van der Waals materials with high anisotropy: geometrical and optical approaches

Light: Science & Applications
The emergence of van der Waals (vdW) materials resulted in the discovery of their high optical, mechanical, and electronic anisotropic properties, immediately enabling countless novel phenomena and applications.
Aleksandr S. Slavich, Georgy A. Ermolaev, Mikhail K. Tatmyshevskiy, Adilet N. Toksumakov, Olga G. Matveeva, Dmitriy V. Grudinin, Kirill V. Voronin, Arslan Mazitov, Konstantin V. Kravtsov, Alexander V. Syuy, Dmitry M. Tsymbarenko, Mikhail S. Mironov, Sergey M. Novikov, Ivan Kruglov, Davit A. Ghazaryan, Andrey A. Vyshnevyy, Aleksey V. Arsenin, Valentyn S. Volkov, Kostya S. Novoselov   +18 more
doaj   +1 more source

Dimeric dipeptide mimetics of BDNF loop 4 are potential antidepressants with novel mechanisms of action

Фармакокинетика и Фармакодинамика
This review covers original research focused on the design, synthesis, and pharmacological evaluation of an innovative dimeric dipeptide mimetic of brain-derived neurotrophic factor (BDNF) loop 4 bis-(N-monosuccinyl-L-seryl-L-lysine) hexamethylenediamide
T. A. Gudasheva, P. Yu. Povarnina, A. V. Tarasyuk, V. P. Zherdev, A. D. Durnev   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source