Results 91 to 100 of about 13,194 (271)
Insulin stimulates glucose uptake in adipocytes by triggering translocation of glucose transporter 4-containg vesicles to the plasma membrane. Under basal conditions, these vesicles (IRVs for insulin-responsive vesicles) are retained inside the cell via ...
A. B. Meriin+3 more
doaj +1 more source
Psychotria ipecacuanha, is a plant species with known medicinal properties that is critically endangered due to overexploitation of natural populations.
Simone Da Silva+3 more
semanticscholar +1 more source
The Antiviral Activity of Polyphenols
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard+5 more
wiley +1 more source
A short introduction illustrates the concept of chiral economical syntheses and the advantages of the corresponding approaches. Using the total synthesis of emetine according to the work of Openshaw and Whittaker and the total synthesis of the steroid ...
A. Fischli
doaj +1 more source
New Diagnostic and Therapeutic Targets for Spinal Cord Injury: GRN Gene
ABSTRACT Spinal cord injury (SCI) is a severe disabling disease due to the poor self‐healing of the central nervous system. Studies showed that many N6‐methyladenosine (m6A) RNA methylation profiles are hypomethylated after SCI, which are related to neural regeneration and different m6A marker genes.
Han Ding+6 more
wiley +1 more source
Identification of Novel Antiviral Compounds Targeting Entry of Hantaviruses
Hemorrhagic fever viruses, among them orthohantaviruses, arenaviruses and filoviruses, are responsible for some of the most severe human diseases and represent a serious challenge for public health.
Jennifer Mayor+3 more
doaj +1 more source
The novel and highly pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), has become a continued focus of global attention due to the serious threat it poses to public health.
Zhonglei Wang, Zhonglei Wang, Liyan Yang
doaj +1 more source
Drug repurposing approach against chikungunya virus: an in vitro and in silico study
The chikungunya virus (CHIKV) is an alphavirus transmitted by Aedes mosquitoes. There are no licenced antivirals or vaccines for treatment or prevention. Drug repurposing approach has emerged as a novel concept to find alternative uses of therapeutics to
Bhagyashri Kasabe+8 more
doaj +1 more source
Canavanine Inhibits Vimentin Assembly But Not Its Synthesis in Chicken Embryo Erythroid Cells [PDF]
In chicken embryo erythroid cells, newly synthesized vimentin first enters a Triton X-100 (TX-100)-soluble pool and subsequently assembles posttranslationally into TX-100-insoluble vimentin filaments (Blikstad I., and E. Lazarides, J. Cell Biol., 96:1803-
Lazarides, Elias, Moon, Randall T.
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