Results 91 to 100 of about 13,194 (271)

Inhibitors of RNA and protein synthesis cause Glut4 translocation and increase glucose uptake in adipocytes

open access: yesScientific Reports, 2022
Insulin stimulates glucose uptake in adipocytes by triggering translocation of glucose transporter 4-containg vesicles to the plasma membrane. Under basal conditions, these vesicles (IRVs for insulin-responsive vesicles) are retained inside the cell via ...
A. B. Meriin   +3 more
doaj   +1 more source

Emetine and cephaeline production and regulation by in vitro propagation of Psychotria ipecacuanha (Brot.) Stokes in semi-solid media and temporary immersion bioreactor

open access: yes, 2020
Psychotria ipecacuanha, is a plant species with known medicinal properties that is critically endangered due to overexploitation of natural populations.
Simone Da Silva   +3 more
semanticscholar   +1 more source

The Antiviral Activity of Polyphenols

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard   +5 more
wiley   +1 more source

Chirale Ökonomie

open access: yesCHIMIA, 1976
A short introduction illustrates the concept of chiral economical syntheses and the advantages of the corresponding approaches. Using the total synthesis of emetine according to the work of Openshaw and Whittaker and the total synthesis of the steroid ...
A. Fischli
doaj   +1 more source

New Diagnostic and Therapeutic Targets for Spinal Cord Injury: GRN Gene

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 15, August 2025.
ABSTRACT Spinal cord injury (SCI) is a severe disabling disease due to the poor self‐healing of the central nervous system. Studies showed that many N6‐methyladenosine (m6A) RNA methylation profiles are hypomethylated after SCI, which are related to neural regeneration and different m6A marker genes.
Han Ding   +6 more
wiley   +1 more source

Identification of Novel Antiviral Compounds Targeting Entry of Hantaviruses

open access: yesViruses, 2021
Hemorrhagic fever viruses, among them orthohantaviruses, arenaviruses and filoviruses, are responsible for some of the most severe human diseases and represent a serious challenge for public health.
Jennifer Mayor   +3 more
doaj   +1 more source

NEW USES FOR EMETINE [PDF]

open access: yesSouthern Medical Journal, 1915
n ...
openaire   +1 more source

Turning the Tide: Natural Products and Natural-Product-Inspired Chemicals as Potential Counters to SARS-CoV-2 Infection

open access: yesFrontiers in Pharmacology, 2020
The novel and highly pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), has become a continued focus of global attention due to the serious threat it poses to public health.
Zhonglei Wang, Zhonglei Wang, Liyan Yang
doaj   +1 more source

Drug repurposing approach against chikungunya virus: an in vitro and in silico study

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The chikungunya virus (CHIKV) is an alphavirus transmitted by Aedes mosquitoes. There are no licenced antivirals or vaccines for treatment or prevention. Drug repurposing approach has emerged as a novel concept to find alternative uses of therapeutics to
Bhagyashri Kasabe   +8 more
doaj   +1 more source

Canavanine Inhibits Vimentin Assembly But Not Its Synthesis in Chicken Embryo Erythroid Cells [PDF]

open access: yes, 1983
In chicken embryo erythroid cells, newly synthesized vimentin first enters a Triton X-100 (TX-100)-soluble pool and subsequently assembles posttranslationally into TX-100-insoluble vimentin filaments (Blikstad I., and E. Lazarides, J. Cell Biol., 96:1803-
Lazarides, Elias, Moon, Randall T.
core  

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