Results 121 to 130 of about 2,288,906 (387)

THE ROLE OF TCF7L2 TRANSCRIPTION FACTOR IN THE FUCTION OF THALAMO-CORTICAL CIRCUITS AND IN PATHOGENESIS OF AUTISM SPECTRUM DISORDER

open access: yesIBRO Neuroscience Reports, 2023
Katarzyna Hryniewiecka   +5 more
doaj   +1 more source

Targeting Multilayered Metabolic Networks in Brain Diseases: Emerging Perspectives on Nanodelivery Strategies

open access: yesAdvanced Science, EarlyView.
Brain diseases involve multilayered metabolic disruptions that reshape cellular interactions and microenvironments. This review outlines core metabolic features across disease states and presents emerging nanodelivery strategies as precision tools to reprogram pathological metabolism.
Jingyi Zhou, Chen Jiang
wiley   +1 more source

An Agent-Based Model of Collective Emotions in Online Communities

open access: yes, 2010
We develop a agent-based framework to model the emergence of collective emotions, which is applied to online communities. Agents individual emotions are described by their valence and arousal.
A. Chmiel   +23 more
core   +2 more sources

Variations of Aberrant Volume, Activity, and Network Connectivity of Hippocampus in Adolescent Male Rats Exposed to Juvenile Stress

open access: yesBrain Sciences
Background: Childhood is a crucial period for brain development, and short-term juvenile stress has demonstrated long-lasting effects on cognitive and cellular functions in the hippocampus.
Aoling Cai   +5 more
doaj   +1 more source

Synergistic Modulation of Microglial Polarization by Acteoside and Ferulic Acid via Dual Targeting of Nrf2 and RORγt to Alleviate Depression‐Associated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Machine‐learning‐directed phytochemical pair ACT/FA, administered at BDD's orthodox ratio, synergistically modulates microglial polarization via dual Nrf2/RORγt targeting to attenuate neuroinflammation and depressive behaviors. This concentration‐dependent synergism replicates the parent formula's efficacy while providing a mechanistic basis for ...
Dongjing Guo   +7 more
wiley   +1 more source

Modeling Emotion Influence from Images in Social Networks [PDF]

open access: yes, 2014
Images become an important and prevalent way to express users' activities, opinions and emotions. In a social network, individual emotions may be influenced by others, in particular by close friends.
Cai, Lianhong   +3 more
core  

Mesenchymal Stromal Cells Play an Analgesic Role Through a Npy2r Sensory Neuron‐Mediated Lung‐to‐Brain Axis

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang   +25 more
wiley   +1 more source

Operationalising “loveability”: an interdisciplinary approach to enriching quality of life experiences in cities through creative cultural spaces

open access: yesFrontiers in Built Environment
Loveability represents an emerging answer for enriching urban quality of life. The idea prioritises city dwellers’ emotional connections with psycho-spatial aspects of cities, beyond mere infrastructure, functionality, or services (“liveability”), which ...
Mizan Rambhoros   +3 more
doaj   +1 more source

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