Results 101 to 110 of about 144,338 (247)

Protective effects of neutrophil serine protease inhibition against ischemia–reperfusion injury in lung or heart transplantation

open access: yesThe FEBS Journal, EarlyView.
A major complication of organ transplantation is primary graft dysfunction, which represents the leading cause of early post‐transplantation morbidity and mortality. Pre‐operative depletion of neutrophil serine proteases in circulating neutrophils by pretreatment with a cathepsin C inhibitor in recipients could prevent early post‐operative ...
Sevil Korkmaz‐Icöz   +6 more
wiley   +1 more source

Exome‐based genotype‐first reverse phenotyping using structured electronic health record data identifies novel SERPINA1 variants associated with liver markers and demonstrates a dominant effect for specific variants on liver phenotype

open access: yesHepatology Research, EarlyView.
Overview of the exome‐based genotype‐first reverse phenotyping approach targeting SERPINA1. The schematic illustrates key pathways, including cytolysis, cholestasis, and liver synthesis, alongside clinical and biological phenotyping through data extraction and an exome‐wide association approach.
Maël Silva Rodriguez   +11 more
wiley   +1 more source

Impact of sulfonamide allergy label on clinical outcomes of acute cystitis: a retrospective matched cohort study

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Cystitis is a common infection in an otherwise healthy individual. Sulfonamide antibiotics are first‐line treatment options. Sulfonamide allergy label (SAL) is the second most common antibiotic allergy label in electronic health records, yet its impact on clinical outcomes in patients with cystitis is not well‐characterised.
Ray Moussa   +3 more
wiley   +1 more source

A Qualitative Exploration of Healthcare Workers' Experiences of End of Life Care for People With an Intellectual Disability

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To explore healthcare workers' experiences of end of life care for people with an intellectual disability. Design A descriptive qualitative study. Method Semi‐structured interviews were conducted with 28 healthcare workers who cared for older people with an intellectual disability at their end of life.
Mary McCarron   +3 more
wiley   +1 more source

Infection risk in atopic dermatitis patients treated with biologics and JAK inhibitors: BioDay results

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This cohort study of 1793 atopic dermatitis patients (aged ≥ 12) found higher infection rates with Janus kinase inhibitor treatment compared to biologic treatment, particularly for herpes infections, with a history of viral or fungal skin infection as a risk factor associated with infection.
Lian F. van der Gang   +22 more
wiley   +1 more source

Delayed traumatic subcutaneous emphysema: a case report. [PDF]

open access: yesJ Med Case Rep
Bishop L, MacLaren S, Pollitt W.
europepmc   +1 more source

Assessment of Diagnostic Tools to Detect Acute Gas Bubble Disease in Atlantic Salmon (Salmo salar L.)

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Currently, diagnosis of gas bubble disease (GBD) in fish relies on visual observations of bubbles in various body parts and exophthalmus. These observations lack quantified information about gas bubble load, limiting their diagnostic value.
S. Stensby‐Skjærvik   +9 more
wiley   +1 more source

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