Results 41 to 50 of about 218,651 (379)

Improving Lung Function in Severe Heterogenous Emphysema with the Spiration Valve System (EMPROVE). A Multicenter, Open-Label Randomized Controlled Clinical Trial

American Journal of Respiratory and Critical Care Medicine, 2019
Rationale: Less invasive, nonsurgical approaches are needed to treat severe emphysema. Objectives: To evaluate the effectiveness and safety of the Spiration Valve System (SVS) versus optimal medical management.
G. Criner, A. Delage, K. Voelker, D. Hogarth, A. Majid, Michael A. Zgoda, D. Lazarus, R. Casal, S. Benzaquen, R. Holladay, A. Wellikoff, K. Calero, M. Rumbak, P. Branca, M. Abu-Hijleh, J. Mallea, R. Kalhan, A. Sachdeva, C. Kinsey, C. Lamb, M. Reed, W. Abouzgheib, Phillip V. Kaplan, Gregory X. Marrujo, D. Johnstone, M. Gasparri, A. Meade, Christopher A. Hergott, C. Reddy, R. Mularski, A. Case, S. Makani, R. Shepherd, Benson Chen, G. Holt, S. Martel   +35 more
semanticscholar   +1 more source

Visual Emphysema at Chest CT in GOLD Stage 0 Cigarette Smokers Predicts Disease Progression: Results from the COPDGene Study.

Radiology, 2020
Background The clinical significance of visually evident emphysema on CT images in individuals without spirometric evidence of chronic obstructive pulmonary disease (COPD) by current diagnostic criteria is, to the knowledge of the authors, unknown ...
A. Oh, M. Strand, K. Pratte, E. Regan, S. Humphries, J. Crapo, D. Lynch   +6 more
semanticscholar   +1 more source

Fleischner Society Visual Emphysema CT Patterns Help Predict Progression of Emphysema in Current and Former Smokers: Results from the COPDGene Study.

Radiology, 2020
Background The correlation between visual emphysema patterns and subsequent progression of disease may provide a way to enrich a study population for treatment trials of emphysema.
Bilal El Kaddouri, M. Strand, D. Baraghoshi, S. Humphries, J. Charbonnier, E. V. van Rikxoort, D. Lynch   +6 more
semanticscholar   +1 more source

長期間喫煙による気管支唱息,肺気腫の病態的変化 [PDF]

, 2004
The influence of long-term cigarette smoking on the pathophysiology of chronic respiratory diseases with obstructive ventilatory dysfunction was discussed in patients with asthma and pulmonary emphysema (PE). 1.
Ashida, Kozo, Fujii, Makoto, Hamada, Masanori, Hosaki, Yasuhiro, Iwagaki, Naofumi, Mitsunobu, Fumihiro, Takata, Shingo, Tanizaki, Yoshiro   +7 more
core   +1 more source

Isolation of slow-cycling cancer cells from lung patient-derived xenograft using carboxyfluorescein-succinimidyl ester retention-mediated cell sorting

STAR Protocols, 2023
Summary: The slow-cycling subpopulation plays an important role in anticancer drug resistance and tumor recurrence. Here, we describe a clinically relevant patient-derived xenograft model and a carboxyfluorescein succinimidyl ester dye that is diluted in
Jaebeom Cho, Hye-Young Min, Ho-Young Lee
doaj  

The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells

Nature Communications, 2016
The binding of tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to nicotinic acetylcholine receptors (nAChRs) induces calcium signalling.
Hye-Jin Boo, Hye-Young Min, Hyun-Ji Jang, Hye Jeong Yun, John Kendal Smith, Quanri Jin, Hyo-Jong Lee, Diane Liu, Hee-Seok Kweon, Carmen Behrens, J. Jack Lee, Ignacio I. Wistuba, Euni Lee, Waun Ki Hong, Ho-Young Lee   +14 more
doaj   +1 more source

n-3系脂肪散を強化した食事療法が有効と考えられた肺気腫の一例 [PDF]

, 1998
An effective treatment for the advanced stages of chronic obstructive pulmonary disease (COPD) has not been established yet. We report our recent experience of one patient with pulmonary emphysema treated by dietary supplementation of n-3 fatty acid for ...
Ashida, Kozo, Hosaki, Yasuhiro, Mifune, Takashi, Mitsunobu, Fumihiro, Okamoto, Makoto, Tanizaki, Yoshiro, Tsugeno, Hirofumi, Tsuji, Takao   +7 more
core   +1 more source

Deep Learning Enables Automatic Classification of Emphysema Pattern at CT.

Radiology, 2019
BackgroundPattern of emphysema at chest CT, scored visually by using the Fleischner Society system, is associated with physiologic impairment and mortality risk.PurposeTo determine whether participant-level emphysema pattern could predict impairment and ...
S. Humphries, A. Notary, J. P. Centeno, M. Strand, J. Crapo, E. Silverman, D. Lynch   +6 more
semanticscholar   +1 more source

Risk factors of pneumothorax and chest tube placement after computed tomography-guided core needle biopsy of lung lesions : a single-centre experience with 822 biopsies [PDF]

, 2018
Purpose: To determine the risk factors of pneumothorax and chest tube placement after computed tomography-guided core needle lung biopsy (CT-CNB). Material and methods: Variables that could increase the risk of pneumothorax and chest tube placement were ...
Gokalp, Gokhan, Ozturk, Kerem, Soylu, Esra, Topal, Ugur   +3 more
core   +1 more source

The impact of emphysema on surgical outcomes of early-stage lung cancer: a retrospective study

BMC Pulmonary Medicine, 2019
Background The presence of emphysema on computed tomography (CT) is associated with an increased frequency of lung cancer, but the postoperative outcomes of patients with pulmonary emphysema are not well known.
Seijiro Sato, Masaya Nakamura, Yuki Shimizu, Tatsuya Goto, Terumoto Koike, Hiroyuki Ishikawa, Masanori Tsuchida   +6 more
doaj   +1 more source