Basilar Predominant Emphysema: Thinking beyond Alpha-1-Antitrypsin Deficiency
Case Reports in Medicine, 2022 Basilar predominant emphysema, or disproportionate emphysematous involvement of the lung bases compared to the apices, is an uncommon radiographic pattern of emphysema traditionally associated with alpha-1-antitrypsin deficiency (AATD). We present a case
Ho-Man Yeung, Lauren Gaffaney
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American Journal of Respiratory and Critical Care Medicine, 2019 Rationale: Less invasive, nonsurgical approaches are needed to treat severe emphysema. Objectives: To evaluate the effectiveness and safety of the Spiration Valve System (SVS) versus optimal medical management.
G. Criner +35 more
semanticscholar +1 more source
Risk factors of pneumothorax and chest tube placement after computed tomography-guided core needle biopsy of lung lesions : a single-centre experience with 822 biopsies [PDF]
, 2018 Purpose: To determine the risk factors of pneumothorax and chest tube placement after computed tomography-guided core needle lung biopsy (CT-CNB). Material and methods: Variables that could increase the risk of pneumothorax and chest tube placement were ...
Gokalp, Gokhan +3 more
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Empyema necessitans and a persistent air leak associated with rupture of an anaerobic lung abscess due to bacteroides [PDF]
, 2017 No abstract ...
Blyth, Kevin G., Sharma, Varun
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Quantitative CT analysis in patients with pulmonary emphysema: is lung function influenced by concomitant unspecific pulmonary fibrosis? [PDF]
, 2019 Purpose: Quantitative analysis of CT scans has proven to be a reproducible technique, which might help to understand the pathophysiology of chronic obstructive pulmonary disease (COPD) and combined pulmonary fibrosis and emphysema.
Doellinger, Felix +5 more
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Endothelial HIF-2α as a Key Endogenous Mediator Preventing Emphysema.
American Journal of Respiratory and Critical Care Medicine, 2020 RATIONALE Endothelial injury may provoke emphysema, but molecular pathways of disease development require further discernment. Emphysema lungs exhibit decreased expression of hypoxia inducible factor-2α (HIF-2α)-regulated genes, and tobacco smoke ...
S. Pasupneti +11 more
semanticscholar +1 more source
Nature Communications, 2016 The binding of tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to nicotinic acetylcholine receptors (nAChRs) induces calcium signalling.
Hye-Jin Boo +14 more
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New Spirometry Indices for Detecting Mild Airflow Obstruction. [PDF]
, 2018 The diagnosis of chronic obstructive pulmonary disease (COPD) relies on demonstration of airflow obstruction. Traditional spirometric indices miss a number of subjects with respiratory symptoms or structural lung disease on imaging.
Barjaktarevic, Igor +13 more
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Radiology, 2020 Background The clinical significance of visually evident emphysema on CT images in individuals without spirometric evidence of chronic obstructive pulmonary disease (COPD) by current diagnostic criteria is, to the knowledge of the authors, unknown ...
A. Oh +6 more
semanticscholar +1 more source
Differentiating Smoking-Related Interstitial Fibrosis (SRIF) from Usual Interstitial Pneumonia (UIP) with Emphysema Using CT Features Based on Pathologically Proven Cases. [PDF]
PLoS ONE, 2016 To differentiate smoking-related interstitial fibrosis (SRIF) from usual interstitial pneumonia (UIP) with emphysema on CT in combined pulmonary fibrosis and emphysema (CPFE) patients.This study was approved by the institutional review board and informed
Kum Ju Chae +7 more
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