Results 41 to 50 of about 213,364 (422)
Recommendations for the use of endoscopic lung volume reduction in South Africa: Role in the treatment of emphysema [PDF]
, 2015 Emphysema is a very common cause of morbidity and mortality in South Africa (SA). Therapeutic options in severe emphysema are limited. Endoscopic lung volume reduction (ELVR) is increasingly being used internationally for the treatment of advanced ...
Allwood, BW +9 more
core +1 more source
A circadian based inflammatory response – implications for respiratory disease and treatment
Sleep Science and Practice, 2017 Circadian clocks regulate the daily timing of many of our physiological, metabolic and biochemical functions. The immune system also displays circadian oscillations in immune cell count, synthesis and cytokine release, clock gene expression in cells and ...
Maria Comas +8 more
doaj +1 more source
Association between plasma sRAGE and emphysema according to the genotypes of AGER gene
BMC Pulmonary Medicine, 2022 Background Higher soluble receptor for advanced glycation end product (sRAGE) levels are considered to be associated with severe emphysema. However, the relationship remains uncertain when the advanced glycation end-product specific receptor (AGER) gene ...
Sooim Sin +4 more
doaj +1 more source
Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16INK4a. [PDF]
, 2019 We previously reported that the canonical innate immune receptor toll-like receptor 4 (TLR4) is critical in maintaining lung integrity. However, the molecular mechanisms via which TLR4 mediates its effect remained unclear.
Ardito, Taylor +10 more
core +1 more source
Thoracic Cancer, Volume 13, Issue 23, Page 3384-3392, December 2022., 2022 In ES‐SCLC under etoposide‐platinum‐atezolizumab, 6‐month survival was 68.6%. In survival analysis for OS, lactate dehydrogenase (LDH), c‐reactive protein (CRP), and forced vital capacity (%) were significant factors. In multivariate analysis for PFS, sex, and LDH were significant. Abstract Background The phase III trial IMpower133 showed that platinum
Jeong Uk Lim +7 more
wiley +1 more source
Radiology, 2020 Background The correlation between visual emphysema patterns and subsequent progression of disease may provide a way to enrich a study population for treatment trials of emphysema.
Bilal El Kaddouri +6 more
semanticscholar +1 more source
Thoracic Cancer, Volume 13, Issue 24, Page 3459-3466, December 2022., 2022 The present study showed that size of targeted lesion, especially diameter ≥20 mm, the bronchus sign, and detection on EBUS imaging were significant contributors to making the diagnosis of lung cancer by TBB with EBUS‐GS. In addition, the odds ratio (OR) of detection on EBUS imaging for the diagnosis of lung cancer with EBUS‐GS tended to be higher than
Yuki Kurihara +11 more
wiley +1 more source
Basilar Predominant Emphysema: Thinking beyond Alpha-1-Antitrypsin Deficiency
Case Reports in Medicine, 2022 Basilar predominant emphysema, or disproportionate emphysematous involvement of the lung bases compared to the apices, is an uncommon radiographic pattern of emphysema traditionally associated with alpha-1-antitrypsin deficiency (AATD). We present a case
Ho-Man Yeung, Lauren Gaffaney
doaj +1 more source
, 2004 The influence of long-term cigarette smoking on the pathophysiology of chronic respiratory diseases with obstructive ventilatory dysfunction was discussed in patients with asthma and pulmonary emphysema (PE). 1.
Ashida, Kozo +7 more
core +1 more source