Results 21 to 30 of about 124,570 (215)
Comparison between cigarette smoke-induced emphysema and cigarette smoke extract-induced emphysema [PDF]
, 2015 Background Emphysema is the main pathological feature of COPD and also is the focus of the related research. Although several emphysema animal models have been established, exact comparison of findings is seldom.
Hong-Liang Zhang +6 more
core +1 more source
Molecular Cancer, 2018 Background Both the type I insulin-like growth factor receptor (IGF1R) and Src pathways are associated with the development and progression of numerous types of human cancer, and Src activation confers resistance to anti-IGF1R therapies. Hence, targeting
Ho Jin Lee +8 more
doaj +1 more source
Pulmonary Emphysema: Visual Interpretation and Quantitative Analysis
대한영상의학회지, 2021 Pulmonary emphysema is a cause of chronic obstructive pulmonary disease. Emphysema can be accurately diagnosed via CT. The severity of emphysema can be assessed using visual interpretation or quantitative analysis.
Jihang Kim
doaj +1 more source
Clinical and Translational Medicine, 2022 Background Programmed death‐ligand 1 (PD‐L1) has functional roles in cancer stem‐like cell (CSC) phenotypes and chemoresistance besides immune evasion.
Hye‐Young Min +14 more
doaj +1 more source
Polymers and inflammation: disease mechanisms of the serpinopathies [PDF]
, 2008 Members of the serpin (serine proteinase inhibitor) superfamily play a central role in the control of inflammatory, coagulation, and fibrinolytic cascades.
David A. Lomas +4 more
core +1 more source
Association between plasma sRAGE and emphysema according to the genotypes of AGER gene
BMC Pulmonary Medicine, 2022 Background Higher soluble receptor for advanced glycation end product (sRAGE) levels are considered to be associated with severe emphysema. However, the relationship remains uncertain when the advanced glycation end-product specific receptor (AGER) gene ...
Sooim Sin +4 more
doaj +1 more source
Nature Communications, 2016 The binding of tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to nicotinic acetylcholine receptors (nAChRs) induces calcium signalling.
Hye-Jin Boo +14 more
doaj +1 more source
Basilar Predominant Emphysema: Thinking beyond Alpha-1-Antitrypsin Deficiency
Case Reports in Medicine, 2022 Basilar predominant emphysema, or disproportionate emphysematous involvement of the lung bases compared to the apices, is an uncommon radiographic pattern of emphysema traditionally associated with alpha-1-antitrypsin deficiency (AATD). We present a case
Ho-Man Yeung, Lauren Gaffaney
doaj +1 more source
Effects of Lung Volume Reduction Surgery on Gas Exchange and Breathing Pattern During Maximum Exercise [PDF]
, 2008 Background: The National Emphysema Treatment Trial studied lung volume reduction surgery (LVRS) for its effects on gas exchange, breathing pattern, and dyspnea during exercise in severe emphysema.
Criner, Gerard J. +6 more
core +1 more source
Differentiating Smoking-Related Interstitial Fibrosis (SRIF) from Usual Interstitial Pneumonia (UIP) with Emphysema Using CT Features Based on Pathologically Proven Cases. [PDF]
PLoS ONE, 2016 To differentiate smoking-related interstitial fibrosis (SRIF) from usual interstitial pneumonia (UIP) with emphysema on CT in combined pulmonary fibrosis and emphysema (CPFE) patients.This study was approved by the institutional review board and informed
Kum Ju Chae +7 more
doaj +1 more source